Therapeutic Targets Database
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TTD Drug ID: DAP000010

Drug Information
NameMirtazapine
SynonymsMLS000759460; 6-Azamianserin; SAM001246659; Mirtazepine; Axit; (N-methyl-11C)mirtazapine; 85650-52-8; L001294; 5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(15),8(13),9,11,16,18-hexaene; EINECS 288-060-6; NCGC00025346-02; Mirtazapinum [INN-Latin]; Mirtabene; CHEMBL654; Norset; Mundogen brand of mirtazapine; Remeron SolTab; AC1Q3ZYM; PDSP1_001529; I06-0606; MLS001076676; Azamianserin; ME-2040; Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-; M0443_SIGMA; BRD-A64977602-001-01-9; Mirtazon; Mepirzepine; Zispin; UNII-A051Q2099Q; Mirtazapine [USAN:INN:BAN]; Mirtazapina; AC1L1HND; Remergil; Remeron; CHEBI:6950; Remeron (TN); C035133; D00563; MolPort-003-849-233; CPD000466347; I01-1882; STK711107; SMR000466347; HMS2052H03; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; Mirtazapina [INN-Spanish]; 2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; Rexer; LS-127703; Mirtazapinum; Mirtazapine (JAN/USAN/INN); Mepirzapin; PDSP2_001513; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine; AC-15480; (1)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine; Organon brand of mirtazapine; 61337-67-5; DB00370; mirtazapine; CID4205; 82601-27-2; Org-3770; Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-; Avanza; Promyrtil; Celltech brand of mirtazapine; LS-185067; Mirtazapine [USAN:BAN:INN]; Mirtazipine; C07570; ORG 3770; Mirtaz; Remergon
Trade NameAfloyan; Arintapin; Arintapina; Avanza; Avanza SolTab; Axit; Calixta; Ciblex; Combar; Comenter; Esprital; Miralix; Mirazep; Miro; Miron; Mirtabene; Mirtachem; Mirtadepi; Mirtal; Mirtalich; Mirtapax; Mirtaron; Mirtastad; Mirtawin; Mirtaz; Mirtazapin; Mirtazapina; Mirtazen; Mirtazep; Mirtazon; Mirtel; Mirzagen; Mirzalux; Mirzaten; Mirzaten Q-Tab; Mitrazen; Mizapin; Mizapin Sol; Norset; Noxibel; Remergil; Remergil SolTab; Remergon; Remergon SolTab; Remeron; Remeron SolTab; Remirta; Rexer; Tazapin; Valdren; Vastat; Zapex; Zicomber; Zispin; Zispin SolTab; Amirel; Divaril; Promyrtil; Zuleptan; Alphamirt; Alphazagen; Finmirtaza; Finpharma; Finscope; Genamirt; Hexazipin; Loxozapin; Medizapin; Mirtacur; Mirtamerck; Mirtapharm; Mirtalphagen; Mirtamed; Mirtapin; Mirtaratio; Mirtaril; Mirtascope; Mirtasole; Mirtastada; Mirtatifi; Mirtatsapiini; Mirtazon; Mirtoral; Mirzaten; Pharmasole; Pharmazepine; Tarzapine; Tazascope; Tirzamed; Loxozapin; Mirta; Mirtagamma; Mirtapin; Mirtazepin; Mirtazelon; Mirtazza; Bexzis; Mirap; Tazamel; Zismirt; Zistap.
CompanyOrganon International
IndicationDepression
[ICD9: 311   ICD10: F32]
Approved    [1]
Structure

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InChI1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-1
8-17(14)20/h2-8,16H,9-12H2,1H3
InChIKeyRONZAEMNMFQXRA-UHFFFAOYSA-N
Canonical SMILESCN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4    
Therapeutic ClassAntidepressive Agents
CAS NumberCAS 61337-67-5
FormulaC17H19N3
PubChem Compound IDCID 4205.
PubChem Substance IDSID 9773.
ChEBI6950;
SuperDrug ATC IDN06AX11
SuperDrug CAS ID061337675;
Target5-hydroxytryptamine 2C receptorAntagonist[2][3]
Ref 1Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. To Reference
Ref 2Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Mol Pharmacol. 2008 Mar;73(3):748-57. Epub 2007 Dec 14. To Reference
Ref 3Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies. Therapie. 2005 Sep-Oct;60(5):441-60. To Reference



 

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