Therapeutic Targets Database
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TTD Drug ID: DAP000021

Drug Information
NameDiazepam
SynonymsLA 111; Amiprol; Valrelease; Caudel; Condition; Valuzepam; Faustan,; Usempax ap; WY-3467; Iazepam; Mentalium; ZINC00006427; LA-111; T-quil; EINECS 207-122-5; Diazepam solution; Calmocitene; Diazepam Desitin; Methyl diazepinone; Ansiolin; Prozepam; Radizepam; Novo-Dipam; CHEBI:49575; Doval; Valaxona; Dipaz; Azedipamin; Metamidol; Sibazon; Kiatrium; Ruhsitus; Spectrum3_001780; Methyldiazepinone; Sipam; Nervium; Placidox 10; Lamra; Winii; Paxel; NSC 169897; 1-Methyl-5-phenyl-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Arzepam; Best [Pharaceutical]; NINDS_000967; Gihitan; 5-24-04-00300 (Beilstein Handbook Reference); Euphorin P; neurolytr il; DB07699; Sonacon; S.a. r.l.; I06-0194; Methyldiazepinone (pharmaceutical); A3662/0155188; HSDB 3057; Diaquel; Diazepamum [INN-Latin]; Seduksen; Diazepan leo; Ro 5-2805; Nivalen; Faustal; Diapax; Diazepam (JP15/USP/INN); Nerozen; Umbrium; SMR000058398; Q-pam; Diazepamu; NSC-77518; MLS000759402; KBioGR_001012; Quetinil; Diazepam-ratiopharm; Paralium; Apaurin; Baogin; Dipam; Saromet; Diazepam Dak; Apo-diazepam; KBio3_002780; Diazetard; Serenack; Quiatril; Lembrol; Paxum; AC1L1EZE; Diapam; 7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Mandro-Zep; NCGC00178168-01; Diacepan; 53320-84-6; NSC77518; Liberetas; Servizepam; Unisedil; Neurolytril; Paceum; diazepam; 7-Chloro-1-methyl-5-3H-1,4-benzodiazepin-2(1H)-one; Diazepam [USAN:INN:BAN:JAN]; BRD-K16508793-001-01-8; Ortopsique; Diazepam Nordic; 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one; Velium; Serenzin; Trazepam; S.A. R.L; Plidan; Serenamin; Diastat Acudial; Eridan; Kratium; Assival; Trankinon; Sico Relax; DZP; Sedipam; Nellium; 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one; Pms-Diazepam; Anxionil; Evacalm; La-Iii; CB 4261; SAM001246536; Diazemulus; Vival; Placidox 2; 7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one; Lovium; Vatran; Anxicalm; Stesolid; Reliver; CHEMBL12; D0899_SIGMA; e-Pam; Zipan; Valitran; Wy 3467; Britazepam; Mandro; Diazepam Fabra; Tranimul; Sedapam; Gubex; Vivol; Freudal; NSC169897; Dizac; Dienpax; Dipezona; D-Pam; Novazam; Vazen; Kratium 2; STK735517; Relaminal; Ansiolisina; Metil Gobanal; Methyldiazepinone, pharmaceutical; Valeo; BSPBio_003279; Gradual; Vanconin; Diazepan; Diatran; Faustan; Quievita; Diazepam Rectubes; 11100-37-1; Diazepam-Eurogenerics; Duxen; Nixtensyn; Simasedan; AC-10561; Diazepam-Lipuro; Alboral; Spectrum4_000576; Stesolin; Spectrum5_001890; 7-Chloro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one; Diastat; Valium; Tensium; Setonil; Q-Pam Relanium; Diazepam Elmu; D9900_SIGMA; Seduxen; nchembio747-comp27; Paranten; Dupin; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-; Notense; Jinpanfan; Tranquirit; Domalium; Bialzepam; Alupram; Diazepam Intensol; Kabivitrum; Ansilive; HMS503A15; Psychopax; Relanium; Calmaven; Dialar; CPD000058398; Calmociteno; Tensopam; Benzopin; Tranquase; An-Ding; Medipam; AKOS003367969; Ducene; CID3016; C06948; Diastat (TN); Atilen; Mandrozep; Apozepam; Gewacalm; Cercine; Diazapam; DB00829; Bensedin; nchembio.307-comp2; Dialag; UNII-Q3JTX2Q7TU; BIDD:PXR0158; D00293; Levium; DEA No. 2765; Morosan; IDI1_000967; Ro 5-2807; Renborin; Novodipam; BIDD:GT0105; 7-Chloro-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepine; Disopam; Drenian; Tranqdyn; Valiquid; 439-14-5; Pomin; Lizan; Vazepam; HMS2051N04; Ceregulart; Frustan; Aliseum; ProPAM; Calmpose; LS-122; Betapam; D003975; Tranquo-puren; Eurosan; Desconet; Paxate; D9900_FLUKA; Valium (TN); Elcion CR; Chuansuan; Oprea1_126223; Sibazone; Diazemuls; Diapine; Diazepamum; Diazepamu [Polish]; Antenex; Diazem; Centrazepam; BRN 0754371; Atensine; Zepaxid; Desloneg; Parzam; Placidox 5; Calmod; Diaceplex; Solis; Duksen; LA III; DivK1c_000967; MolPort-001-729-114; CCRIS 6009; Noan; Armonil; Diazepam Stada; Tranquo-tablinen; WLN: T67 GNV JN IHJ CG G1 KR; KBio1_000967; Valium R; Diazepin
Trade NameAntenex; Ducene; Valium; Valpam; Diastat; Diazemuls; Anxol; Calmod; Calmpose; Paxum; Starlium; Zepose; Zycalm; Anxicalm; Stesolid; D-Pam; Propam; Pamlin; Benzopin; Betapam; Doval; Pax; Dialar; Diazemuls; Rimapam; Stesolid; Tensium; Valclair;
CompanyHoffmann-La Roche pharmaceutical company
IndicationPain, Anesthesia and Anxiety
[ICD9: 300, 338,780   ICD10: F40-F42, R52, G89]
Approved    [1]
Structure

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InChI1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-
3-2-4-6-11/h2-9H,10H2,1H3
InChIKeyAAOVKJBEBIDNHE-UHFFFAOYSA-N
Canonical SMILESCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3    
Therapeutic ClassAnalgesics
CAS NumberCAS 439-14-5
FormulaC16H13ClN2O
PubChem Compound IDCID 3016.
PubChem Substance IDSID 9163.
ChEBI49575;
SuperDrug ATC IDN05BA01
SuperDrug CAS ID000439145;
TargetGamma-aminobutyric acid-type A (GABAA) receptorAgonist[2][3][4]
Ref 1What every dentist should know about the "z-sedatives". J Mass Dent Soc. 2007 Fall;56(3):44-5. To Reference
Ref 2Mini Rev Med Chem. 2007 Nov;7(11):1108-19.Privileged structures: a useful concept for the rational design of new lead drug candidates. To Reference
Ref 3Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. To Reference
Ref 4The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics. Expert Opin Investig Drugs. 2005 May;14(5):601-18. To Reference



 

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