Therapeutic Targets Database
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TTD Drug ID: DAP000024

Drug Information
NameMethylphenidate
SynonymsMeridil; Metadate CD; Ritalin LA; C07196; DEA No. 1724; Ritalin-SR; Daytrana (TN); Methylin; Methyl phenidyl acetate; Centredin; EINECS 204-028-6; MolPort-001-779-620; Methylfenidan; Methylphenidate [INN:BAN]; Metilfenidato; alpha-Phenyl-2-piperidineacetic acid methyl ester; Plimasine; 4311/B Ciba; Methyl alpha-phenyl-alpha-2-piperidinylacetate; Methylin ER; Metilfenidato [Italian]; nchembio.2007.55-comp28; Ritalin SR; Phenidylate; Centedein; alpha-Phenyl-alpha-(2-piperidyl)acetic acid methyl ester; methyl phenyl(piperidin-2-yl)acetate; 2-Piperidineacetic acid, alpha-phenyl-, methyl ester; DB00422; .alpha.-Phenyl-2-piperidineacetic acid methyl ester; CHEBI:6887; CHEMBL796; C 4311; Methylphenidate (USAN/INN); Metadate; 2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester; D04999; Methylphenidatum [INN-Latin]; Methyl alpha-phenyl-alpha-(2-piperidyl)acetate; Calocain; AC1L1HJM; methyl 2-phenyl-2-piperidin-2-ylacetate; DB06701; 113-45-1; Metadate ER; Centedrin; Tsentedrin; HSDB 3126; Methylphenidatum; Daytrana; 298-59-9 (hydrochloride); Methyl phenidate; Metilfenidato [INN-Spanish]; LS-565; Methyl (2-phenyl-2-(2-piperidyl)acetate); Methylphenidan; Methyl phenidylacetate; Methylofenidan; PMS-Methylphenidate; METHYLPHENIDATE (SEE ALSO: METHYLPHENIDATE HYDROCHLORIDE, CAS 298-59-9, NTPNO 10266-R); CID4158; Ritaline; L001307; MethyPatch; Riphenidate; Methylphen; methylphenidate; UNII-207ZZ9QZ49; NCI-C56280; Concerta; d-methylphenidate HCl; Ritcher works; Ritalin
Trade NameRitalin; Attenta; Methylin; Metadate ER; Equasym; Rubifen; Motiron; Concerta; Ritalin LA; Biphentin; Daytrana
CompanyNovartis
IndicationAttention deficit hyperactivity disorder
[ICD9: 314.0   ICD10: F90]
Approved    [1]
Traumatic brain injury
[ICD9: 800, 801, 803, 804, 850-854   ICD10: S06]
Phase IV    [2]
Structure

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InChI1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-
4,7-8,12-13,15H,5-6,9-10H2,1H3
InChIKeyDUGOZIWVEXMGBE-UHFFFAOYSA-N
Canonical SMILESCOC(=O)C(C1CCCCN1)C2=CC=CC=C2    
Therapeutic ClassCentral Nervous System Stimulants
CAS NumberCAS 113-45-1
FormulaC14H19NO2
PubChem Compound IDCID 4158.
PubChem Substance IDSID 9405.
ChEBI6887;
SuperDrug ATC IDN06BA04
SuperDrug CAS ID000113451;
TargetSodium-dependent dopamine transporterBlocker[3]
Sodium-dependent dopamine transporterBlocker[4]
Ref 1Effects of methylphenidate on the catecholaminergic system in attention-deficit/hyperactivity disorder. J Clin Psychopharmacol. 2008 Jun;28(3 Suppl 2):S46-53. To Reference
Ref 2Autism spectrum disorders: emerging pharmacotherapy. Expert Opin Emerg Drugs. 2005 Aug;10(3):521-36. To Reference
Ref 3Imaging the effects of methylphenidate on brain dopamine: new model on its therapeutic actions for attention-deficit/hyperactivity disorder. Biol Psychiatry. 2005 Jun 1;57(11):1410-5. Epub 2005 Jan 12. To Reference
Ref 4Emerging treatments for traumatic brain injury. Expert Opin Emerg Drugs. 2009 Mar;14(1):67-84. To Reference



 

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