Therapeutic Targets Database
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TTD Drug ID: DAP000061

Drug Information
NamePhenobarbital
Synonyms5-Ethyl-5-phenyl-pyrimidine-2,4,6-trione; Chinoin; Euneryl; DivK1c_000987; Fenemal; Austrominal; Sedonal (sedative); 50-06-6; Valprin 50-PB; Nirvonal; Luramin; D00506; HSDB 3157; 5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione; Pharmetten; Seda-Tablinen; I06-0652; Helional; component of Primatene P; Haplopan; Dormina; Parkotal; Aephenal; Somnosan; Noptil; Stental Extentabs; Lephebar; CCRIS 502; Phenobarb; AC1L1IWE; Phenyral; Luminal; Talpheno; Tridezibarbitur; component of Tedral; Luminal (TN); 57-30-7 (mono-hydrochloride salt); Calminal; Phenonyl; Sedofen; Starilettae; Bialminal; IDI1_000987; Barbivis; Phenylethylmalonylurea; Levsin PB Drops and Tablets; Lixophen; Episedal; Chardonna-2; Thenobarbital; Nova-Pheno; Solfoton talpheno; component of Slowten; Phenylethyl barbituric acid; Phenyletten; Haplos; DB01174; component of Valpin 50-PB; Somnoletten; Stental; LS-135; Hysteps; Somnolens; Triphenatol; Sedicat; Aphenylbarbit; Phenemal; CHEMBL40; Ensodorm; seda-tabl inen; Solu-Barb; Epilol; Cratecil; Fenylettae; NSC9848; Fenobarbitale [DCIT]; Fenobarbital [INN-Spanish]; Phenobarbituric acid; Sedabar; Barbilehae (barbilettae); Phenomet; Starifen; Hypnogen; C07434; Barbophen; Linasen; Promptonal; Elixir of phenobarbital; 46755-67-3; Solfoton; Phen-Bar; SK-Phenobarbital; MolPort-001-783-066; barbilehae; Pamine PB; Ensobarb; Sedonal; Bartol; phenobarbital (PB); Lumesyn; Phenobarbitalum [INN]; EINECS 200-007-0; Cabronal; Lumofridetten; theominal; UNII-YQE403BP4D; Doscalun; Antrocol; barbellon; Eskabarb; Nunol; Barbonal; Hennoletten; 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione; Teoloxin; Lumen; Agrypnal; Hypno-Tablinetten; AI3-02726; Phenobarbitone; 5-Ethyl-5-phenylbarbituric acid; Cardenal; Aphenyletten; Fenobarbital; Versomnal; Donphen; d ezibarbitur; Zadoletten; le phebar; Phenylethylbarbitursaeure; Barbiphenyl; HMS503E15; Dormiral; Phenylethylbarbituric acid; NINDS_000987; Theoloxin; phenobarbital; Neurobarb; Dormital; Sevenal; Sombutol; MolPort-003-959-166; barbellen; NCGC00159493-03; Duneryl; Sedophen; Sedonettes; Phenylaethylbarbitursaeure; 5-Ethyl-5-phenyl-2,4,6-pyrimidinetrione; Fenobarbitale; Coronaletta; CID4763; Liquital; Gardenal; Hypnoltol; Epidorm; 11097-06-6; Hypnaletten; Triabarb; Damoral; 5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione; Phenobal; Phenobarbitol; PUBERTAL PHENOBARBITAL STUDY; Phenobarbitalum; Gustase-Plus; Oprea1_384816; Luphenil; Lubrokal; Phenobarbyl; 5-Ethyl-5-phenyl-2,4,6-(1H,3H,5H)pyrimidinetrione; Acido 5-fenil-5-etilbarbiturico; Barbiphen; Acido 5-fenil-5-etilbarbiturico [Italian]; NSC128143; Barbita; phenylral; component of Hecadrol; Lepinaletten; Phenobarbital (JP15/USP/INN); Leonal; KBio1_000987; Adonal; Phenemalum; Amylofene; NSC 128143; Spasepilin; Phazyme-PB; P1636_SIGMA; SMR000058986; Bardorm; Lepinal; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-; Phenyl-ethyl-barbituric acid; Lefebar; Dezibarbitur; Calmetten; Phenolurio; Zadonal; Teolaxin; CHEBI:8069; Phenobarbitonum; Glysoletten; Somonal; Barbituric acid, 5-ethyl-5-phenyl-; component of Bronkotabs; Sedlyn; Arco-Lase Plus; Barbinal; Fenbital; Lumesettes; Phenaemal; Phenobarbital, Monosodium Salt; Gardepanyl; aephe nal; BIDD:PXR0061; WLN: T6VMVMV FHJ F2 FR; component of Antrocol; Henotal; MLS001240232; Barbipenyl; Phenobarbital [USAN:INN:JAN]; Hypnolone; Hypnette; BAS 00226811; AKOS000605404; Phenylethylbarbiturate; Epanal; PHOB; barbapil; NCGC00159493-02; DEA No. 2285; Phenobarbitalum [INN-Latin]; Codibarbita; Molinal; Lubergal; Fenosed; stental exte ntabs; Etilfen; Barbipil; Barbenyl; Blu-phen; Phenoluric; Phenoturic; Polcominal; InChI=1/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17; Sedizorin; 5-Phenyl-5-ethylbarbituric acid; Epsylone; fen osed
Trade NameLuminal
CompanyFISCHER and ROCH
IndicationSeizures
[ICD9: 345.9, 780.3   ICD10: G40, P90, R56]
Approved    [1]
Structure

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InChI1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-
7H,2H2,1H3,(H2,13,14,15,16,17)
InChIKeyDDBREPKUVSBGFI-UHFFFAOYSA-N
Canonical SMILESCCC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2    
Therapeutic ClassAnticonvulsants
CAS NumberCAS 50-06-6
FormulaC12H12N2O3
PubChem Compound IDCID 4763.
PubChem Substance IDSID 9638.
ChEBI8069;
SuperDrug ATC IDN03AA02
SuperDrug CAS ID000050066;
TargetGamma-aminobutyric acid receptorAntagonist[2][3]
Ref 1What is phenobarbital used for?: Intermediate. 2004. To Reference
Ref 2DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. To Reference
Ref 3Anticonvulsant drugs: mechanisms of action. Adv Neurol. 1986;44:713-36. To Reference



 

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