Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000068

Drug Information
NameRopinirole
SynonymsRopinirole (INN); 2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-; Ropinirole [INN:BAN]; Lopac0_001101; SKF 101468; BRD-K15933101-003-01-2; 91374-21-9; NCGC00096064-01; SK&F-101,468; Ropinirolum [INN-Latin]; UNII-030PYR8953; 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one; 4-[2-(Dipropylamino)ethyl]indoline-2-one; Ropinirole; SKF 101468; BIDD:GT0826; Ropitor; CHEMBL589; NCGC00096064-02; MolPort-003-666-598; SPECTRUM1505178; Ropinirol [INN-Spanish]; Ropitor (TN); D08489; ropinirol; L000520; AC1L1JLL; NCGC00015893-01; ReQuip XL; CID5095; C07564; CHEBI:8888; AB1004799; TL8005859; LS-83890; Lopac-R-4152; Ropinirolum; 2H-Indol-2-one, 4-[2-(dipropylamino)ethyl]-1,3-dihydro-; DB00268; I06-0692; 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one; HMS2093K04; SK&F 101468; ropinirole; ReQuip CR; 4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one; NCGC00015893-04; 91374-20-8 (hydrochloride)
Trade NameRequip; Ropark; Adartrel
CompanyGlaxoSmithKline plc
IndicationParkinson's disease
[ICD9: 332   ICD10: F02.3, G20]
Approved    [1]
Structure

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InChI1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-
15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)
InChIKeyUHSKFQJFRQCDBE-UHFFFAOYSA-N
Canonical SMILESCCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1    
Therapeutic ClassAntiparkinson Agents
CAS NumberCAS 91374-21-9
FormulaC16H24N2O
PubChem Compound IDCID 5095.
PubChem Substance IDSID 9767.
ChEBI8888;
SuperDrug ATC IDN04BC04
SuperDrug CAS ID091374219;
TargetD(2) dopamine receptorAgonist[2][3]
D(2) dopamine receptorMultitarget[2][3]
D(3) dopamine receptorAgonist[2][3]
D(3) dopamine receptorMultitarget[2][3]
Ref 1Update on ropinirole in the treatment of Parkinson's disease. Neuropsychiatr Dis Treat. 2009;5:33-6. Epub 2009 Apr 8. To Reference
Ref 2The relevance of dopamine agonists in the treatment of depression. Neuropsychiatr. 2009;23(1):15-25. To Reference
Ref 3Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD. Br J Pharmacol. 2002 Jun;136(4):620-8. To Reference



 

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