Therapeutic Targets Database
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TTD Drug ID: DAP000079

Drug Information
NameZiprasidone
SynonymsZiprasidone mesylate trihydrate; ziprasidona; 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one; DB00246; I14-0766; UNII-6UKA5VEJ6X; CP-88,059-1; C21H21ClN4OS; Zipradon (TN); CP-88,059-01; 2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-; ziprazidone; MolPort-003-850-885; ziprasidonum; CPD000466328; Geodon; SAM001246607; Zipradon; CP 88059-01; CP-88,059; CID60854; Ziprasidone [INN:BAN]; Ziprasidone hydrochloride; MLS000759435; CHEBI:10119; Ziprasidone; Ambap122883-93-6; AC1L1U27; C07568; 5-{2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one; CP 88059; 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one; BIDD:GT0042; CHEMBL708; CP-88059-1; TL8000889; 146939-27-7; 138982-67-9 (hydrochloride monohydrate); D08687; L000659; SMR000466328; Ziprasidone (INN); 6-chloro-5-[2-[4-(7-thia-8-azabicyclo[4.3.0]nona-1,3,5,8-tetraen-9-yl)piperazin-1-yl]ethyl]-1,3-dihydroindol-2-one; Zeldox; LS-83744
Trade NameGeodon; Zeldox
CompanyPfizer
IndicationSchizophrenia
[ICD9: 295   ICD10: F20]
Approved    [1]
Structure

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InChI1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-
9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(
H,23,27)
InChIKeyMVWVFYHBGMAFLY-UHFFFAOYSA-N
Canonical SMILESC1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54    
Therapeutic ClassAntipsychotic Agents
CAS NumberCAS 146939-27-7
FormulaC21H21ClN4OS
PubChem Compound IDCID 60854.
PubChem Substance IDSID 9771.
ChEBI10119;
SuperDrug ATC IDN05AE04
SuperDrug CAS ID146939277;
TargetD(2) dopamine receptorAgonist[2]
Ref 1Emerging anxiolytics. Expert Opin Emerg Drugs. 2007 Nov;12(4):541-54. To Reference
Ref 2Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone). J Clin Psychopharmacol. 2008 Dec;28(6):608-17. To Reference



 

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