Therapeutic Targets Database
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TTD Drug ID: DAP000143

Drug Information
NameMinoxidil
SynonymsNCGC00179672-01; 38304-91-5; Bio2_000585; EU-0100786; Prestwick_521; SMR000326812; KBio1_000160; 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide; Minossidile [Italian]; SAM002589949; DivK1c_000160; SGCUT00112; MLS000028566; MINOXIDIL (FOR WOMEN); Spectrum4_000063; KBio2_002673; Spectrum3_000509; Rogaine for Men; Rogaine for Women; Bio2_000105; AC1L1HN1; Theroxidil; SPECTRUM1500415; nchembio.79-comp10; CHEMBL609587; Minoximen; LS-135040; Riup (TN); Spectrum_000969; NCGC00024666-01; MINOXIDIL (FOR MEN); CPD000058963; KBioGR_000585; S1383_Selleck; BRN 0886240; NCGC00024666-05; HMS2091F20; NCGC00018278-01; ZINC00001735; NCGC00015673-04; Rogaine Extra Strength for Men; Loniten; Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide; SPBio_001006; SPBio_001980; CHEBI:49774; Rogaine; KBio3_000210; to_000070; Minoxidil (USP/INN); Bio1_001062; MolPort-003-666-236; 2,4-Diamino-6-piperidino-pyrimidine-3-oxide; KBio2_004017; 5-25-12-00317 (Beilstein Handbook Reference); AB00513797; BPBio1_000065; NCGC00015673-02; C9H15N5.H2O; HMS1920P03; Pfizer Brand of Minoxidil; Normoxidil; Prestwick3_000020; Prestwick0_000020; Alostil; Spectrum5_001299; Minoxigaine; CAS-38304-91-5; HMS1989F07; Prexidil; 2,4-Diamino-6-piperidinopyrimidine 3-oxide; 2,6-Diamino-4-piperidinopyrimidin-1-oxid; Gen-Minoxidil; NCGC00024666-02; minoxidil; KBio2_005241; Spectrum2_001053; 2,4-Diamino-6-piperidinilpirimidina-3-ossido; 2,4-Diamino-6-piperidinilpirimidina-3-ossido [Italian]; Bio1_000573; Men's Rogaine; Tocris-0583; KBio3_000209; 6-[1-Piperidinyl]pyrimidine-2,4-diamine 3 oxide; 2,4-Diamino-6-piperidinopyrimidine 3-N-oxide; D00418; NCGC00024666-06; SMR000058963; Minoxidil Pfizer Brand; DB00350; CHEMBL802; HMS1361F07; 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide; NCGC00015673-01; MLS001077294; Lopac0_000786; BSPBio_002037; Neoxidil; KBio3_001537; KBio2_000105; Tricoxidil; Bio1_000084; Minoxidil [USAN:BAN:INN]; HMS2089L08; EINECS 253-874-2; 6-Piperidino-2,4-diaminopyrimidine 3-oxide; SBB056986; KBioGR_000105; NCGC00015673-11; Alopexil; Regaine; M1389; 16317-69-4; NCGC00024666-07; BCBcMAP01_000193; CPD-7668; ROGAINE EXTRA STRENGTH (FOR MEN); TM-160; NCGC00024666-03; HMS1791F07; 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine; Pierminox; CHEBI:6942; Mens Rogaine Foam; MINOXIDIL EXTRA STRENGTH (FOR MEN); Men s Rogaine Foam; AC-5271; NCGC00024666-08; U-10858; MLS000859953; ROGAINE (FOR WOMEN); RiUP; KBioSS_001449; Prestwick1_000020; D008914; BRD-K14888893-001-02-3; NINDS_000160; BSPBio_000059; BSPBio_001385; HMS500H22; HMS1568C21; DB08225; HSDB 6538; Jsp006715; Rogaine, Regaine, Avacor and Mintop, Minoxidil; KBio2_001449; Minoxidilum [INN-Latin]; M 4145; NCGC00024666-04; IDI1_033855; Minossidile; U-10,858; KBioSS_000105; Prestwick2_000020; Trocoxidil; CID4201; Lopac-M-4145; Apo-Gain; MINOXIDIL EXTRA STRENGTH FOR MEN; KBio2_006585; 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine; IDI1_000160; 2,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine; BRD-K06902185-001-05-2; MolPort-005-932-694; Minoxidilum; CBiol_001798; Rogaine (TN); Lonolox; SMP1_000192; ROGAINE (FOR MEN); Ambap38304-91-5; 6-(piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide; 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine; Minodyl; Loniten (TN); U 10858
Trade NameRogaine; Regaine
CompanyUpjohn Corporation
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1
-5,10H2
InChIKeyZIMGGGWCDYVHOY-UHFFFAOYSA-N
Canonical SMILESC1CCN(CC1)C2=NC(=N)N(C(=C2)N)O    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 38304-91-5
FormulaC9H15N5O
PubChem Compound IDCID 4201.
PubChem Substance IDSID 179263.
ChEBI6942;
SuperDrug ATC IDC02DC01; D11AX01
SuperDrug CAS ID038304915;
TargetATP-sensitive potassium channelOpener[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071344 To Reference
Ref 2Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil. J Invest Dermatol. 2001 Dec;117(6):1594-600. To Reference
Ref 3Clinical pharmacokinetics of vasodilators. Part I. Clin Pharmacokinet. 1998 Jun;34(6):457-82. To Reference



 

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