Therapeutic Targets Database
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TTD Drug ID: DAP000158

Drug Information
NameMoxifloxacin
SynonymsDB00218; CHEMBL32; 186826-86-8; MXF; LS-141510; (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; CID152946; 151096-09-2; AC1L49EP; moxifloxacin; I06-1961; Avelox I.V.; UNII-U188XYD42P; BAY 12-8039 (*Hydrochloride*); Actira (*Hydrochloride*); CCRIS 8690; Moxifloxacin [INN:BAN]; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-; MFX; Avelox (*Hydrochloride*); Vigamox; 192927-63-2; Avelox; 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid; MXFX
Trade NameAvelox; Avalox; Avelon; Vigamox
CompanyBayer AG
IndicationBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
Approved    [1]
Structure

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InChI1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12
)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6
,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1
InChIKeyFABPRXSRWADJSP-MEDUHNTESA-N
Canonical SMILESCOC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O    
Isomeric SMILESCOC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Therapeutic ClassAnti-Bacterial Agents
CAS NumberCAS 354812-41-2
FormulaC21H24FN3O4
PubChem Compound IDCID 152946.
PubChem Substance IDSID 625376.
SuperDrug ATC IDJ01MA14; S01AE07
SuperDrug CAS ID151096092;
TargetDNA topoisomerase IIInhibitor[2]
DNA topoisomerase IIMultitarget[2]
Topoisomerase IVInhibitor[2]
Topoisomerase IVMultitarget[2]
Ref 1Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8. To Reference
Ref 2Quinolones as enhancers of camptothecin-induced cytotoxic and anti-topoisomerase I effects. Biochem Pharmacol. 2008 Mar 15;75(6):1272-81. Epub 2007 Dec 3. To Reference



 

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