Therapeutic Targets Database
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TTD Drug ID: DAP000190

Drug Information
NameCiprofloxacin
SynonymsUNII-5E8K9I0O4U; C17H18FN3O3; CCRIS 5241; DivK1c_000095; BAY q 3939; Cipro I.V.; SPBio_002065; Ciprofloxacino; BRD-K04804440-311-02-3; ARONIS020379; ciprofloxacin; Bay-09867; Cifloxin; Ciprofloxacin hydrochloride; Ciflox; BSPBio_003344; MLS001336035; 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid; Fimoflox; Ciprodar; CPFX; Ciprofloxacino [INN-Spanish]; Prestwick1_000113; BAY-Q-3939; Cipro (TN); Proksi 500; HMS2093I03; KBio3_002846; Proflox; Spectrum_000162; 17850_FLUKA; Ciprofloxacine; BIDD:GT0205; Cixan; Cycin; Ciprecu; Prestwick0_000113; Spectrum3_001872; Bi-Cipro; D00186; Alcon Cilox; IDI1_000095; 3-Quinolinecarboxylic acid,1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl); KBioGR_001567; Velomonit; AC-7613; 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; Quinolid; SMP1_000125; Ipiflox; NCGC00095058-02; KBio2_003210; Cipromycin; Ciprofloxacinum [INN-Latin]; Ciprofloxacin monohydrochloride; 1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; Ciplus; AC1L1EEW; 33434_RIEDEL; 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID; CAS-93107-08-5; CID2764; CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER; Ciprobay; Ciprobay Uro; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid; Sophixin Ofteno; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-; Baflox; KBio1_000095; Cipro IV; Ciprolin; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O; CHEBI:100241; Superocin; HMS1922E18; Septicide; 33434_FLUKA; Ciproxan; SPBio_001474; Ciprofloxacin (JAN/USP/INN); KBio2_005778; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; BAS 06989041; Ciproxina; BRN 3568352; Ciprofloxacin [USAN:INN:BAN]; AKOS000269653; Corsacin; Ciprolon; Cipro XR; HSDB 6987; Rancif; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-; Ciprocinol; Cilab; Ciprofloxacine [INN-French]; Spectrum2_001567; 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; Ciprofloxacin Hydrchloride; Proksi 250; Cyprobay; Ciproquinol; Spectrum5_001089; Liposomal-ciprofloxacin; Prestwick2_000113; NINDS_000095; Ciprowin; Proflaxin; NCGC00095058-01; CRL-1605 & Ciprofloxacin; HMS2090O07; BSPBio_000126; Eni; 85721-33-1; Probiox; Bay o 9867 (*Hydrochloride*); KBio2_000642; NCGC00178128-01; MolPort-000-819-654; STK021082; Baycip; Quintor; CPF; CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER; Ciproxine; Spitacin; BPBio1_000140; Oprea1_313572; SPECTRUM1503614; Cipro; Ciproxin; BAYQ3939; CHEMBL8; Loxan; Cipro (*Hydrochloride*); Bio-0540; Bacquinor; Prestwick3_000113; Flociprin; Unex; Ciprofloxacina; Cipro XL; SMR000471901; LS-141563; Ciprofloxacin HCl; NSC620634; Bernoflox; Zumaflox; Bay o 9867; Citopcin; Ciprofloxacinum; DB00537; Spectrum4_000874; Ciprogis; Roxytal; nchembio820-comp1; Ciprofloxacin dihydrochloride; Italnik; 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid; C05349; NCGC00016959-01; CBMicro_048498; Ciloxan (*Hydrochloride*); HMS500E17; Oprea1_008239; Ciprinol; Ciriax; Ciproflox; KBioSS_000642
Trade NameCiloxan; Cipro; Cipro XR; Cipro XL Ciproxin; Proquin; Ciproflox; Ciprofloxacino; Cidrax.
CompanyBayer Pharmaceuticals Corporation
IndicationBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
Approved    [1]
Structure

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InChI1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-
10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
InChIKeyMYSWGUAQZAJSOK-UHFFFAOYSA-N
Canonical SMILESC1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O    
Therapeutic ClassAnti-Infective Agents
CAS NumberCAS 85721-33-1
FormulaC17H18FN3O3
PubChem Compound IDCID 2764.
PubChem Substance IDSID 7727.
SuperDrug ATC IDJ01MA02; S01AE03; S02AA15; S03AA07
SuperDrug CAS ID085721331;
TargetDNA topoisomerase IIInhibitor[2]
DNA topoisomerase IIMultitarget[2]
Topoisomerase IV subunit AInhibitor[2]
Topoisomerase IV subunit AMultitarget[2]
Ref 1How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. To Reference
Ref 2Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro. Antimicrob Agents Chemother. 1988 Aug;32(8):1182-6. To Reference



 

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