Therapeutic Targets Database
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TTD Drug ID: DAP000230

Drug Information
NameMeperidine
SynonymsD008614; IDI1_000983; HSDB 3116; Pethidinum; Ethyl 1-methyl-4-phenylisonipecotate; LS-85121; Pethidine (INN); 610593_ALDRICH; 1-Methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester; CID4058; Meperidol; Operidine EPJ-I; Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate; 1-Methyl-4-phenyl-piperidin-4-carbon-saeure-aethylester [German]; Pethidineter; Pethanol; Dolosal; C07128; 50-13-5 (hydrochloride); meperidine; 610593_FLUKA; Operidine EPJ I; DB00454; Piperosal; DivK1c_000983; Methyl phenylpiperidine carbonic acid ethyl ester; Lydol; Demarol; 1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester; EINECS 200-329-1; Dolsin; Pipersal; Isonipecain; YIsonipecotic acid, 1-methyl-4-phenyl-, ethyl ester (8CI); 57-42-1; AC1L1HBJ; Demerol; Petidina [INN-Spanish]; Pethidine DBL (TN); N-Methyl-4-phenyl-4-carbethoxypiperidine; MolPort-001-785-564; Phetidine; CHEBI:122528; 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester; KBio1_000983; NINDS_000983; Pethidine; D08343; UNII-9E338QE28F; DEA No. 9230; 4-Carbethoxy-1-methyl-4-phenylpiperidine; Meperidine solution; Pethidinum [INN-Latin]; Nemerol; Lidol; 1-Methyl-4-phenyl-piperidin-4-carbon-saeure-aethylester; Pethidine DBL; Petydyna [Polish]; Petydyna; L000908; 1-Methyl-4-phenylisonipecotic acid, ethyl ester; CHEMBL607; Isonipecotic acid, 1-methyl-4-phenyl-, ethyl ester; Dolcontral; Petidina; Pethidin; Isonipecaine
Trade NameDemerol
CompanyApotex Inc
IndicationAnesthetic
[ICD9: 338   ICD10: R52]
Approved    [1]
Structure

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InChI1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/
h4-8H,3,9-12H2,1-2H3
InChIKeyXADCESSVHJOZHK-UHFFFAOYSA-N
Canonical SMILESCCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2    
Therapeutic ClassAnesthesia
CAS NumberCAS 57-42-1
FormulaC15H21NO2
PubChem Compound IDCID 4058.
PubChem Substance IDSID 9338.
SuperDrug ATC IDN02AB02
SuperDrug CAS ID000057421;
TargetAlpha-2 adrenergic receptorAgonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040110 To Reference
Ref 2Meperidine, remifentanil and tramadol but not sufentanil interact with alpha(2)-adrenoceptors in alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor knock out mice brain. Eur J Pharmacol. 2008 Mar 17;582(1-3):70-7. Epub 2007 Dec 27. To Reference
Ref 3Meperidine exerts agonist activity at the alpha(2B)-adrenoceptor subtype. Anesthesiology. 2002 Jun;96(6):1420-6. To Reference



 

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