Therapeutic Targets Database
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TTD Drug ID: DAP000231

Drug Information
NameClonidine
Synonyms2-(2,6-Dichlorophenylamino)-2-imidazoline; Clonidine [USAN:BAN:INN]; 2-IMIDAZOLINE, 2-(2,6-DICHLOROPHENYLAMINO)-; Clonidine (JAN/USAN/INN); KBio2_004389; NCGC00024734-01; Prestwick0_000248; Clonidinum [INN-Latin]; 2,6-dichloro-N-2-imidazolidinylidenebenzenamide; Bio2_000788; Catapres-TTS; Clonidinhydrochlorid; KBioSS_001821; HMS1791P10; AC1L1EI5; CATAPRES-TTS-1; Clonidinum; BSPBio_001588; KBioSS_000308; CHEBI:46632; M-5041T; NCGC00024734-05; 2-Imidazoline, 2-(2,6-dichloroanilino)-; 2,6-dichloro-N-(2-imidazolidinylidene)aniline; Bio2_000308; nchembio705-10; DivK1c_000774; D00281; Prestwick2_000248; KBio2_000308; CCRIS 7787; 2-[(2,6-dichlorophenyl)imino]-2-imidazoline; Catapresan; 57066-25-8; NCGC00015268-08; CAS-4205-91-8; Prestwick1_000248; BIDD:GT0547; NCGC00024734-04; ST-155BS; KBioGR_000308; 2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI); BSPBio_002055; L000193; nchembio.79-comp11; Chlornidinum; Isoglaucon; Clofenil; Lopac0_000268; Dixarit; 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine; 2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2); Catapressan; SPBio_001233; 2-((2,6-Dichlorophenyl)imino)imidazolidine; SKF 34427; IDI1_000774; 734571A; EINECS 224-119-4; NCGC00015268-01; UNII-MN3L5RMN02; SPBio_002255; Gemiton; KBio2_002876; clonidine; Clonidina; Tocris-0690; AB00514634; HMS1361P10; Catapres- TTS; Klofelin; T171; Duraclon; 2-(2,6-Dichlorophenylimino)imidazolidine; BSPBio_000036; Spectrum3_000358; HMS2089G11; 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-; BRD-K98530306-001-02-1; CHEMBL134; KBio2_005444; CATAPRES-TTS-3; IDI1_034058; Clopheline; ZINC00896484; AC1Q3K6V; NINDS_000774; M 5041T; Clonidina [INN-Spanish]; 2-(2,6-Dichloroanilino)-2-imidazoline; BRD-K98530306-003-05-0; Spectrum4_000956; Lopac-C-7897; Catarpres; CID2803; Spectrum5_000759; Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-; ST-155-BS; KBio2_001821; Spectrum_001341; HSDB 3040; Bio1_001448; NCGC00015268-02; HMS1989P10; LS-79606; CATAPRES-TTS-2; 4205-91-8 (mono-hydrochloride); KBio3_000616; Prestwick3_000248; NCGC00024734-02; 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI); CHEBI:3757; ST 155BS; DB07566; Clonidin; Bio1_000470; KBio2_006957; MolPort-001-779-668; KBio3_001275; Tenso-Timelets; BPBio1_000040; 2,6-dichloro-N-imidazolidin-2-ylideneaniline; AKOS001595470; 4205-90-7; Bio1_000959; Klofenil; Spectrum2_001187; DB00575; Catarpresan; Catarpres-TTS (TN); NCGC00179680-01; N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine; Duraclont; Adesipress; Hemiton; KBio1_000774; Catarpres-TTS; C9H9Cl2N3; KBio3_000615; 2-[(2,6-Dichlorophenyl)imino]imidazoline; MolPort-005-932-374; NCGC00024734-03; KBioGR_001572
Trade NameCatapres
CompanyIntas Pharmaceuticals
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H
2,12,13,14)
InChIKeyGJSURZIOUXUGAL-UHFFFAOYSA-N
Canonical SMILESC1CN=C(N1)NC2=C(C=CC=C2Cl)Cl    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 4205-90-7
FormulaC9H9Cl2N3
PubChem Compound IDCID 2803.
PubChem Substance IDSID 163008.
ChEBI46632;
SuperDrug ATC IDC02AC01; N02CX02; S01EA04
SuperDrug CAS ID004205907;
TargetAlpha-2 adrenergic receptorAgonist[2][3][4]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 070315 To Reference
Ref 2Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats. Pharmacol Biochem Behav. 2000 Nov;67(3):397-403. To Reference
Ref 3The alpha2 -adrenergic receptors in hypertension and heart failure: experimental and clinical studies. J Hypertens. 2001 Dec;19(12):2115-24. To Reference
Ref 4Effects of intrathecal vs. systemic clonidine in treating chronic allodynia-like response in spinally injured rats. Brain Res. 1996 Oct 14;736(1-2):28-34. To Reference



 

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