Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000233

Drug Information
NameDexmedetomidine
SynonymsTocris-2023; MPV-1440; Dexmedetomidinum; CHEMBL778; C07450; (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole; Dexmedetomidine (USAN/INN); DEXMEDETOMIDINE; ZINC04632106; Dexmedetomidina; 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; D00514; 113775-47-6; AC1NSJXT; CID5311068; MPV 1440; NCGC00025347-01; Precedex (TN); 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; CHEBI:4466
Trade NamePrecedex
CompanyHospira, Inc.
IndicationSedation
[ICD9: 338   ICD10: R52]
Approved    [1]
Structure

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InChI1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-
3H3,(H,14,15)/t11-/m0/s1
InChIKeyCUHVIMMYOGQXCV-NSHDSACASA-N
Canonical SMILESCC1=C(C(=CC=C1)C(C)C2=CN=CN2)C    
Isomeric SMILESCC1=C(C(=CC=C1)[C@H](C)C2=CN=CN2)C
Therapeutic ClassHypnotics and Sedatives
CAS NumberCAS 113775-47-6
FormulaC13H16N2
PubChem Compound IDCID 5311068.
PubChem Substance IDSID 9653.
ChEBI4466;
SuperDrug ATC IDN05CM18
N05CM18
TargetAlpha-2 adrenergic receptorAgonist[2][3]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Dexmedetomidine in intensive care unit: a study of hemodynamic changes. Middle East J Anesthesiol. 2002 Oct;16(6):587-95. To Reference
Ref 3alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role. Anaesthesia. 1999 Feb;54(2):146-65. To Reference



 

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