Therapeutic Targets Database
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TTD Drug ID: DAP000235

Drug Information
NameOxymetazoline
SynonymsAfrin Original 12 Hour Pump Mist; oxymeta zoline; NCGC00022345-04; NCGC00022345-05; D08322; KBio2_006667; Visine L.R; IDI1_000567; KBioSS_001531; DB00935; UNII-8VLN5B44ZY; Spectrum5_001114; Oxymetazoline (INN); Prestwick3_000224; Vicks Sinex 12 Hour Ultra Fine Mist for Sinus Relief; FT-0082560; Afrin Extra Moisturizing 12 Hour Nasal Spray; Spectrum_001051; BRD-K16195444-001-01-7; Iliadin; NINDS_000567; 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol; Oxymethazoline; Afrin Original 12 Hour Nasal Spray; AC-6370; NCGC00015766-02; Oximetazolina [INN-Spanish]; 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-6-tert-butyl-phenol; Phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl- (7CI,8CI); CAS-151615; BSPBio_000267; NCGC00015766-03; Vicks Sinex 12 Hour Nasal Spray; SPBio_001095; Genasal Nasal Spray Up to 12 Hour Relief; Drixoral Nasal Solution; Lopac0_000903; KBioGR_000908; Operil (TN); Neo-Synephrine 12 Hour Spray; Afrin Sinus 12 Hour Nasal Spray; Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl- (9CI); Hazol; Nasal Relief 12 Hour Nasal Spray; EINECS 216-079-1; Oxymetazolinum; Phenol, 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-; 6-tert-Butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol; Oximetazolinum; BSPBio_002145; KBio3_001645; 1491-59-4; Navisin; SPBio_002188; D010109; Tocris-1142; CID4636; Phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-; oxymetazoline hydrochloride crystalline; Oxylazine; HMS2089G03; 2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline; CHEMBL762; Duramist Plus Up To 12 Hour Nasal Decongestant Spray; Oximetazolina; Dristan Long Lasting Nasal Mist; Navasin; BPBio1_000419; KBio2_001531; Nostrilla 12 Hour Nasal Decongestant; Afrin Cherry 12 Hour Nasal Spray; NCGC00022345-06; BPBio1_000295; Sinerol; H 990; LS-104146; KBio1_000567; 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol; Prestwick0_000224; NCGC00022345-02; Oxymetazolinum [INN-Latin]; Nafrine; Lopac-O-2378; Spectrum3_000533; BRN 0886303; CHEBI:142520; Oxymetazoline [INN:BAN]; Dristan Long Lasting Mentholated Nasal Spray; Spectrum2_000998; Prestwick2_000224; Prestwick1_000224; MolPort-002-538-313; L000459; Visine L.R.; KBio2_004099; NCGC00015766-10; 6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol; Rhinolitan; nchembio705-11; Afrin Original 12 Hour Nose Drops; Rhinofrenol; C07363; Nezeril; NCGC00015766-01; Spectrum4_000464; Phenol, 3-((4,5-dihydro-1H-imidazol-2-yl)methyl)-6-(1,1-dimethylethyl)-2,4-dimethyl-; DivK1c_000567; oxymetazoline; Oxymetozoline; HSDB 3143; AC1L1IM1; Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-; Biomol-NT_000161
Trade NameDrixoral Decongestant
CompanySchein Pharmaceutical
IndicationNasal congestion
[ICD9: 478.19   ICD10: J34.89]
Approved    [1]
Structure

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InChI1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-
14/h8,19H,6-7,9H2,1-5H3,(H,17,18)
InChIKeyWYWIFABBXFUGLM-UHFFFAOYSA-N
Canonical SMILESCC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C    
Therapeutic ClassNasal Decongestants
CAS NumberCAS 1491-59-4
FormulaC16H24N2O
PubChem Compound IDCID 4636.
PubChem Substance IDSID 9567.
SuperDrug ATC IDR01AA05; R01AB07; S01GA04
SuperDrug CAS ID001491594;
TargetAlpha-2 adrenergic receptorAgonist[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018471 To Reference
Ref 2Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries. Invest Ophthalmol Vis Sci. 2001 Aug;42(9):2049-55. To Reference



 

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