Therapeutic Targets Database
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TTD Drug ID: DAP000241

Drug Information
NameMidazolam
SynonymsMidazolam Base; UC429_SIGMA; 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate; 8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin; Midanium; 59467-70-8; Midosed; Midazolamum; UNII-R60L0SM5BC; Dazolam; Dormicum (TN); ZINC00001732; AC-18749; CHEMBL655; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride; AC1L1HMA; 8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine; Ro 21-3981; BRN 0625572; MolPort-003-849-219; 8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine; Midazolam [INN:BAN:JAN]; LS-77780; C07524; BIDD:GT0647; Versed; TL8003787; EINECS 261-774-5; CID4192; DEA No. 2884; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine; midazolam; C18H13ClFN3; DB00683; 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-; D00550; NCGC00168254-01; Dormicum; Midazolam (JAN/INN); nchembio747-comp32; 4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-; Midazolamum [INN-Latin]
Trade NameDormicum; Hypnovel; Midacum; Versed
CompanyRoche Pharmaceuticals
IndicationSedation
[ICD9: 338   ICD10: R52]
Approved    [1]
Structure

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InChI1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12
(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3
InChIKeyDDLIGBOFAVUZHB-UHFFFAOYSA-N
Canonical SMILESCC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F    
Therapeutic ClassHypnotics and Sedatives
CAS NumberCAS 59467-70-8
FormulaC18H13ClFN3
PubChem Compound IDCID 4192.
PubChem Substance IDSID 9727.
SuperDrug ATC IDN05CD08
SuperDrug CAS ID059467708;
TargetBenzodiazepine receptorAgonist[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 075154 To Reference
Ref 2A comparative study on the effects of the benzodiazepine midazolam and the dopamine agents, apomorphine and sulpiride, on rat behavior in the two-way avoidance test. Pharmacol Biochem Behav. 2009 Apr;92(2):351-6. To Reference



 

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