Therapeutic Targets Database
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TTD Drug ID: DAP000242

Drug Information
NameFlurazepam
SynonymsRo-5-6901/3; NCGC00164573-01; Flurazepam hydrochloride; Felmane; C21H23ClFN3O; Insumin; Dalmadorm; Noctosom; Dalmane; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-, dihydrochloride; BRN 0767925; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-1,3-dihydro-; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-; DEA No. 2767; MolPort-004-285-859; Flurazepam HCL; 7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; LS-34188; UNII-IHP475989U; Flurazepamum; Flurazepamum [INN-Latin]; Felison; CHEMBL968; 17617-23-1; HSDB 3085; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-; Stauroderm; Flurazepam [INN:BAN:JAN]; 7-chloro-1-(2-diethylaminoethyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one; Insumin (TN); D00329; Flurazepam (JP15/INN); 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-1-(2-(diethylamino)ethyl)-5-(o-fluorophenyl)-; 5-24-04-00322 (Beilstein Handbook Reference); 7-Chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 36105-20-1 (mono-hydrochloride); 1172-18-5 (di-hydrochloride); EINECS 241-591-7; Valdorm; Paxane; Dalmane-R; CID3393; AC1L1FU2; flurazepam; DB00690; 7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1H-1,4-benzodiazepin-2(3H)-one; Flunox; Somnol
Trade NameDalmane; Dalmadorm
CompanyWest-ward Pharmaceutical Corp
IndicationInsomnia
[ICD9: 307.41, 307.42, 327.0, 780.51, 780.52   ICD10: F51.0, G47.0]
Approved    [1]
Structure

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InChI1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24
-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3
InChIKeySAADBVWGJQAEFS-UHFFFAOYSA-N
Canonical SMILESCCN(CC)CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F    
Therapeutic ClassHypnotics and Sedatives
CAS NumberCAS 17617-23-1
FormulaC21H23ClFN3O
PubChem Compound IDCID 3393.
PubChem Substance IDSID 171083.
SuperDrug ATC IDN05CD01
SuperDrug CAS ID017617231;
TargetBenzodiazepine receptorAgonist[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 070344 To Reference
Ref 2An epigenetic intervention interacts with genetic strain differences to modulate the stress-induced reduction of flurazepam's antiseizure efficacy in the mouse. Eur Neuropsychopharmacol. 2009 Jun;19(6):398-401. Epub 2009 Feb 1. To Reference



 

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