Therapeutic Targets Database
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TTD Drug ID: DAP000247

Drug Information
NameFormoterol
Synonyms49861-99-6; AC1Q6QRX; 67346-49-0; (+-)-2'-Hydroxy-5'-((RS)-1-hydroxy-2-(((RS)-p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide; Formoterolum [INN-Latin]; CID449974; Formoterolum; formoterol, ((R*,R*)-(+-))-isomer; HSDB 7287; Formamide, N-(2-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, (R-(R*,R*))-; CID3410; AC1MHY5S; UNII-F91H02EBWT; MolPort-003-847-486; formoterol; CHEMBL1363; CID3034756; MolPort-005-934-219; Foradil; eformoterol; Oxis; AC1L1FVE; 183814-29-1; 289657-27-8; NCGC00025167-01; AC1MJ0T4; Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-; (R,R)-Formoterol; Formoterol tartrate; CHEBI:408174; AR-1K3797; Foradile; UNII-5ZZ84GCW8B; LS-187799; DB01274; 128954-45-0; D07990; FORMOTEROL FUMARATE; N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide; AC1MIIFN; Oxis (TN); AC-459; C07805; CID3045233; LS-187368; (-)-Formoterol; N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide; Arformoterol; LS-69501; Formoterol [USAN:INN:BAN]; 299964-45-7; 126587-85-7; BIDD:GT0743; Arformoterol (INN); Tocris-1448; N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide; Oxeze Turbuhaler; Oxeze Turbuhaler Foradil; MOLI000351; 73573-87-2; N-[2-hydroxy-5-[(1S)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide; NCGC00181126-01; MolPort-005-942-483; N-{2-hydroxy-5-[(1R)-1-hydroxy-2-({(1R)-1-methyl-2-[4-(methyloxy)phenyl]ethyl}amino)ethyl]phenyl}formamide; CID3083544; AC1L9NSS; Formoterol (INN); n-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide; 3-formylamino-4-hydroxy-alpha-(N-1-methyl-2-p-methoxyphenethylaminomethyl)benzyl alcohol.hemifumarate; N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide; DB00983; L000259; 208102-40-3; CID9862958; D07463
Trade NameForadil; Foradile; Oxeze; Atock; Atimos Modulite; Perforomist
CompanyNorvatis Phamaceuticals Corporation
IndicationAsthma
[ICD9: 493   ICD10: J45]
Approved    [1]
Structure

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InChI1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18
(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,
21,22)/i2-1
InChIKeyBPZSYCZIITTYBL-JVVVGQRLSA-N
Canonical SMILESCC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O    
Isomeric SMILESCC(CC1=CC=C(C=C1)O[11CH3])NCC(C2=CC(=C(C=C2)O)NC=O)O
Therapeutic ClassSympathomimetic
CAS NumberCAS 73573-87-2
FormulaC19H24N2O4
PubChem Compound IDCID 449974.
PubChem Substance IDSID 340.
SuperDrug ATC IDR03AC13
SuperDrug CAS ID043229807;
TargetBeta-2 adrenergic receptorAgonist[2][3][4]
Ref 1Long duration of airway but not systemic effects of inhaled formoterol in asthmatic patients. Respir Med. 2008 Mar;102(3):449-56. Epub 2007 Nov 19. To Reference
Ref 2Long-acting beta2-agonists for chronic obstructive pulmonary disease patients with poorly reversible airflow limitation. Cochrane Database Syst Rev. 2002;(3):CD001104. To Reference
Ref 3J Pharm Pharmacol. 2000 Nov;52(11):1417-23.Tocolytic effects of a long-acting beta2-adrenoceptor agonist, formoterol, in rats. To Reference
Ref 4Long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2000;(2):CD001104. To Reference



 

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