Therapeutic Targets Database
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TTD Drug ID: DAP000259

Drug Information
NameClonazepam
SynonymsKenoket; EINECS 216-596-2; Iktorivil; Oprea1_168772; LS-34260; DivK1c_000973; KBio1_000973; HMS2093H22; 2-H-1,4-Benzodiazepin-2-one, 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-; 106955-87-7; Lktorivil; D002998; 5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-24-04-00351 (Beilstein Handbook Reference); 2H-1,4-Benzodiazepin-2-one, 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-; CHEMBL452; AC-15733; 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one; LS-34156; 1622-61-3; Ro-5-4023; 1,3-Dihydro-5-(o-chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2-one; NSC179913; Clonopin; HSDB 3265; Klonopin; 5-(2-Chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2(1H)-one; Rivoril; Clonazepam [USAN:INN:BAN:JAN]; UNII-5PE9FDE8GB; Chlonazepam; Cloazepam; DB01068; C15H10ClN3O3; Lonazep; C1277_SIGMA; Clonazepamum; 2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-; 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one; RO4023; 5-(o-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one; Clonazepam (JP15/USP/INN); AC1L1EI2; MolPort-001-729-088; 5-(o-Chlorophenyl)-7-nitro-1H-1,4-benzodiazepin-2(3H)-one; Rivatril; Ro 54023; 5-(2-Chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one; BRN 0759557; 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ro 5-4023; BAS 00308658; Clonex; Ro 4023; CID2802; Solfidin; Rivotril; CHEBI:3756; Ro 4-8180; Alti-Clonazepam; Paxam; DF2374250; DEA No. 2737; I14-1364; IDI1_000973; 1,3-Dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one; WLN: T67 GMV JN IHJ CNW KR BG; Antilepsin; Landsen; Melzap; 3H-1,4-Benzodiazepin-2-one, 1,3-dihydro-5-(o-chlorophenyl)-7-nitro-; NIOSH/DF2374250; ZINC03813003; HMS503C07; 5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one; Jsp003251; Klonopin (TN); Ravotril; NINDS_000973; BIDD:PXR0144; D00280; Ro 5-4023/B-7; Klonopin Rapidly Disintegrating; Antelepsin; NSC 179913; Clonazepamum [INN-Latin]; clonazepam
Trade NameKlonopin; Ravotril; Rivotril; Rivatril
CompanyRoche Pharmaceuticals
IndicationEpilepsy
[ICD9: 345   ICD10: G40]
Approved    [1]
Structure

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InChI1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11
)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)
InChIKeyDGBIGWXXNGSACT-UHFFFAOYSA-N
Canonical SMILESC1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3Cl    
Therapeutic ClassAnticonvulsants
CAS NumberCAS 1622-61-3
FormulaC15H10ClN3O3
PubChem Compound IDCID 2802.
PubChem Substance IDSID 158706.
SuperDrug ATC IDN03AE01
SuperDrug CAS ID001622613;
TargetGamma-aminobutyric acid receptorAgonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074569 To Reference
Ref 2Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. To Reference
Ref 3Hyperekplexia in neonates. Postgrad Med J. 2001 Sep;77(911):570-2. To Reference



 

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