Therapeutic Targets Database
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TTD Drug ID: DAP000271

Drug Information
NameRosiglitazone
SynonymsSpectrum_001703; Gaudil; UNII-05V02F2KDG; 5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione; S00306; STOCK6S-23924; MolPort-002-508-212; 2,4-Thiazolidinedione, 5-004-02-((((methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-; Spectrum2_001241; 5-[[4-[2-(methyl-(2-pyridyl)amino)ethoxy]phenyl]methyl] thiazolidine-2,4-dione; HMS1922J11; 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; DB00412; rosiglitazona; Rosiglizole; [3H]rosiglitazone; AC1L2U9N; NCGC00095124-03; rosiglitazonum; Spectrum4_001125; Gaudil (TN); TDZ 01; Rosi; Brl 49653; Spectrum5_001464; rosiglitazone (Avandia); HSDB 7555; LS-151340; 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-; 2,4-thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-; I06-0141; C18H19N3O3S; NCGC00095124-02; rosiglitazone; BRD-A97437073-001-03-1; Rosiglitazone [INN:BAN]; Brl-49653; 122320-73-4; 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione; Rosiglitazone (INN); KBio2_004751; RSG; 5-((4-(2-Methyl-2-(pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione-2-butenedioate; Spectrum3_000997; D08491; KBio2_007319; Rosigliazone maleate; BRL49653; IDMB (1uM BRL49653, 1uM Dexamethasone, 0.5uM IBMX, 10ug/mL Insulin); Avandia; KBio2_002183; CID77999; KBioGR_001609; Rosigilitazone; KBio3_001913; BRD-A97437073-001-02-3; NCGC00095124-01; KBioSS_002183; SPECTRUM1504263; AC-3459; 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]- (9CI); 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione; BSPBio_002693; RGZ; HMS2094O13; SPBio_001142
Trade NameAvandia
CompanyGSK
IndicationDiabetes mellitus
[ICD9: 250   ICD10: E08-E13]
Approved    [1]
Structure

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InChI1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)1
2-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
InChIKeyYASAKCUCGLMORW-UHFFFAOYSA-N
Canonical SMILESCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3    
Therapeutic ClassHypoglycemic Agents
CAS NumberCAS 122320-73-4
FormulaC18H19N3O3S
PubChem Compound IDCID 77999.
PubChem Substance IDSID 661002.
ChEBI50122;
SuperDrug ATC IDA10BG02
SuperDrug CAS ID122320734;
TargetPeroxisome proliferator activated receptor gammaAgonist[2]
Ref 1New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202. To Reference
Ref 2Functional PPAR-gamma receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas. Nat Med. 2002 Nov;8(11):1281-7. Epub 2002 Oct 15. To Reference



 

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