Therapeutic Targets Database
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TTD Drug ID: DAP000272

Drug Information
NamePioglitazone
SynonymsKBio2_007239; 5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione; Pioglitazonum; AC-1021; Pioglitazone [BAN:INN]; 198077-89-3; Spectrum2_001679; 2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-; D08378; 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI); U 72107A; U 72107; HS-0047; Pioglitazona; Spectrum4_001130; KBioSS_002103; NCGC00163128-01; HMS2089H14; 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; Spectrum3_001002; KBio2_004671; LS-151327; 5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione; HSDB 7322; Pioglitazona [INN-Spanish]; Duetact; Spectrum5_001480; SPBio_001897; I06-0089; CID4829; Actost; 111025-46-8; 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione; (+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione; U-72107; UNII-X4OV71U42S; KBio2_002103; 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-; 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione; Actos (TN); NCGC00163128-02; (+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, (+/-)-; AD-4833; 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, (+-)-; Zactos; Pioglitazone [INN:BAN]; Actos; (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione; BSPBio_002723; KBioGR_001619; C07675; AB1004597; 5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione; BRD-A48430263-003-02-4; Glustin; C19H20N2O3S; CHEBI:8228; CHEMBL595; 105355-27-9; nchembio790-comp10; Spectrum_001623; MolPort-002-508-211; U72,107A; Pioglitazone; pioglitazone (INN); Spectrum5_002067; DB01132; Pioglitazonum [INN-Latin]; AC1L1J1Q; AD 4833; KBio3_001943
Trade NameActos; Glustin; Zactos
CompanyTakeda Pharmaceuticals
IndicationDiabetes mellitus
[ICD9: 250   ICD10: E08-E13]
Approved    [1]
Structure

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InChI1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)1
1-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
InChIKeyHYAFETHFCAUJAY-UHFFFAOYSA-N
Canonical SMILESCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3    
Therapeutic ClassHypoglycemic Agents
CAS NumberCAS 111025-46-8
FormulaC19H20N2O3S
PubChem Compound IDCID 4829.
PubChem Substance IDSID 9877.
ChEBI8228;
SuperDrug ATC IDA10BG03
SuperDrug CAS ID111025468;
TargetPeroxisome proliferator activated receptor gammaAgonist[2]
Ref 1Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes. Curr Drug Targets. 2009 Jan;10(1):71-87. To Reference
Ref 2Functional PPAR-gamma receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas. Nat Med. 2002 Nov;8(11):1281-7. Epub 2002 Oct 15. To Reference



 

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