Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000295

Drug Information
SynonymsCHEMBL519643; C07023; BRL-43694; 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide; CID5284566; 109889-09-0; BIDD:GT0272; AC1NR4P1; granisetron; HMS2089P14; 1-methyl-N-[(1S,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide; Granisetron (USAN/INN); D04370; MolPort-005-943-366
Trade NameKytril
CompanyRoche Pharmaceuticals
IndicationNausea and vomiting
[ICD9: 787, 787.0   ICD10: R11]
Approved    [1]

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Canonical SMILESCN1C2CCCC1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C    
Isomeric SMILESCN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C
Therapeutic ClassAntiemetics
CAS NumberCAS 109889-09-0
PubChem Compound IDCID 5284566.
PubChem Substance IDSID 9235.
SuperDrug ATC IDA04AA02
SuperDrug CAS ID109889090;
Target5-hydroxytryptamine 3 receptorAntagonist[2][3]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2New approaches to chemotherapy-induced nausea and vomiting: from neuropharmacology to clinical investigations. Cancer J. 2006 Sep-Oct;12(5):341-7. To Reference
Ref 3Reduction of rectal sensitivity and post-prandial motility by granisetron, a 5 HT3-receptor antagonist, in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 1993 Apr;7(2):175-80. To Reference


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