Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000307

Drug Information
SynonymsAC-163720; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; MolPort-003-850-185; SR-141716; Acomplia (TN); AC-731; 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-; L000572; DB06155; AC1L2XM5; I06-0381; Acomplia; SR141,716A; Rimonabant (JAN/USAN/INN); Slimona; D05731; SR141716; SR 141716; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; 5-(p-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide; LS-128155; CHEMBL111; Rimonabant; nchembio.552-comp16; SR141716A; Rimoslim; C14319; nchembio.129-comp21; SR-141716A; NCGC00164572-01; ZINC01540228; A 281; UNII-RML78EN3XE; [3H]SR141716A; Rimonabant [USAN:INN]; CID104850; Riobant; 168273-06-1; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; STK642500
Trade NameAcomplia; Bethin; Monaslim; Remonabent; Riobant; Slimona; Rimoslim; Zimulti; Riomont
[ICD9: 278   ICD10: E66]
Withdrawn by EMEA in 2009    [1]

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Canonical SMILESCC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl    
Therapeutic ClassAnti-Obesity Agents
CAS NumberCAS 158681-13-1
PubChem Compound IDCID 104850.
PubChem Substance IDSID 789414.
SuperDrug ATC IDA08AX01
TargetCannabinoid receptor 1Antagonist[2][3][4]
Ref 1Emerging drugs for the treatment of tobacco dependence. Expert Opin Emerg Drugs. 2009 Mar;14(1):23-32. To Reference
Ref 2Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression. Best Pract Res Clin Endocrinol Metab. 2009 Feb;23(1):133-44. To Reference
Ref 3End of the line for cannabinoid receptor 1 as an anti-obesity target? Nat Rev Drug Discov. 2008 Dec;7(12):961-2. To Reference
Ref 4Mini Rev Med Chem. 2007 Nov;7(11):1108-19.Privileged structures: a useful concept for the rational design of new lead drug candidates. To Reference


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