Therapeutic Targets Database
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TTD Drug ID: DAP000355

Drug Information
NameDoxacurium
SynonymsAC1L1SOW; Doxacurii chloridum [Latin]; Chlorure de doxacurium [French]; D00760; AC1L1SOT; Cloruro de doxacurio [Spanish]; Doxacurii chloridum; L000825; DB01135; Chlorure de doxacurium; UNII-M78TVM3G5Z; Nuromax (TN); C07549; Cloruro de doxacurio; 106819-53-8; doxacurium chloride(no stereochemistry); DB01334; Nuromax; CID60168; Doxacurium; AC1Q1RPW; CID60169; AC1Q66PG; bis[3-[6,7,8-trimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] butanedioate dichloride; Doxacurium chloride (USAN/INN); bis[3-[6,7,8-trimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] butanedioate
Trade NameNuromax
CompanyAbbott Laboratories
IndicationSpasms, Pain
[ICD9: 338,780   ICD10: R52, G89]
Approved    [1]
Structure

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InChI1S/C56H78N2O16/c1-57(23-19-37-33-45(65-7)53(69-11)55(71-13)49(37)
39(57)27-35-29-41(61-3)51(67-9)42(30-35)62-4)21-15-25-73-47(59)17
-18-48(60)74-26-16-22-58(2)24-20-38-34-46(66-8)54(70-12)56(72-14)
50(38)40(58)28-36-31-43(63-5)52(68-10)44(32-36)64-6/h29-34,39-40H
,15-28H2,1-14H3/q+2
InChIKeyGBLRQXKSCRCLBZ-UHFFFAOYSA-N
Canonical SMILESC[N+]1(CCC2=CC(=C(C(=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)OC)CCCOC(=O)CCC
(=O)OCCC[N+]4(CCC5=CC(=C(C(=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)OC)C    
Therapeutic ClassAnalgesics
CAS NumberCAS 106819-53-8
FormulaC56H78Cl2N2O16
PubChem Compound IDCID 60169.
PubChem Substance IDSID 9752.
SuperDrug ATC IDM03AC07
SuperDrug CAS ID106819538;
TargetNicotinic acetylcholine receptor alpha subunitAntagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Interaction of nondepolarizing muscle relaxants with M2 and M3 muscarinic receptors in guinea pig lung and heart. Anesthesiology. 1996 Jan;84(1):155-61. To Reference



 

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