Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000367

Drug Information
SynonymsRS-25259-198; RS 25259-198; Palonosetron [INN]; DB00377; AC1L3WNN; 2-Qhbiqo; 135729-61-2; (S-(R*,R*))-2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one; 1H-Benz(de)isoquinolin-1-one, 2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-, (S-(R*,R*))-; CID148211; UNII-5D06587D6R; RS-25259-197; LS-187778; Aloxi; NCGC00166415-02; Onicit; RS-25233-198; NCGC00166415-01; LS-186967; RS 25233-197; RS-25233-197; RS 25259-197; 135729-56-5; 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one; RS 25233-198; (3aR)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one; Palonosetron
Trade NameAloxi
CompanyEisai Inc
IndicationNausea and vomiting
[ICD9: 787, 787.0   ICD10: R11]
Approved    [1]

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Canonical SMILESC1CC2CN(C(=O)C3=C2C(=CC=C3)C1)C4CN5CCC4CC5    
Isomeric SMILESC1C[C@H]2CN(C(=O)C3=C2C(=CC=C3)C1)[C@@H]4CN5CCC4CC5
Therapeutic ClassAntiemetics
CAS NumberCAS 119904-90-4
PubChem Compound IDCID 148211.
PubChem Substance IDSID 725898.
SuperDrug ATC IDA04AA05
Target5-hydroxytryptamine receptor 3AAntagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Management of postoperative nausea and vomiting: focus on palonosetron. Ther Clin Risk Manag. 2009 Feb;5(1):21-34. Epub 2009 Mar 26. To Reference


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