Therapeutic Targets Database
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TTD Drug ID: DAP000370

Drug Information
NameAlfuzosin
SynonymsSL 77499; LS-70106; MLS000759449; NCGC00095152-01; SL 77-499; 2-Furancarboxamide, N-(3-((4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-; AC1L1CWF; SAM001246638; Alfuzosine; KBioGR_001616; MolPort-003-666-623; Alfuzosina; Bio-0003; BSPBio_000323; Alfuzosina [Spanish]; UNII-90347YTW5F; Alfuzosine [French]; Prestwick3_000322; N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide; BPBio1_000357; Alfuzosin (INN); CHEMBL709; 128707-53-9; CHEBI:51141; STK643675; Alfuzosinum [Latin]; Prestwick0_000322; NCGC00095152-05; SPBio_002244; BSPBio_002646; Alfusosine; Prestwick1_000322; DB00346; 86163-78-2; 81403-68-1 (hydrochloride); CPD000466340; NCGC00095152-03; Prestwick2_000322; KBio3_001866; MLS001424027; HMS2051I10; 81403-80-7; HMS1922P11; D07124; alphuzosine; CID2092; Alfuzosin [INN:BAN]; NCGC00095152-02; SMR000466340; L001317; SPECTRUM1505263; alfuzosin; Spectrum5_000817; HMS2093O06; BRD-A09056319-003-03-6; NCGC00095152-04; HSDB 7290; BRD-A09056319-001-02-2; AB00514667; Spectrum3_001063; N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide; Spectrum2_000505; C19H27N5O4; SPBio_000429; N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide; Alfuzosinum; Spectrum4_001208; Xatral (TN)
Trade NameUroxatral; Xatral
CompanySanofi-Aventis
IndicationBenign prostatic hyperplasia
[ICD9: 600   ICD10: N40]
Approved    [1]
Structure

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InChI1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(
27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25
)(H2,20,22,23)
InChIKeyWNMJYKCGWZFFKR-UHFFFAOYSA-N
Canonical SMILESCN(CCCNC(=O)C1CCCO1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 81403-80-7
FormulaC19H27N5O4
PubChem Compound IDCID 2092.
PubChem Substance IDSID 682525.
ChEBI51141;
SuperDrug ATC IDG04CA01
SuperDrug CAS ID081403807;
TargetAlpha-1D adrenergic receptorAntagonist[2]
Ref 1Alpha blockers for the treatment of benign prostatic hyperplasia. Rev Urol. 2007 Fall;9(4):181-90. To Reference
Ref 2Alfuzosin: a review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia. Drugs. 2002;62(4):633-53. To Reference



 

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