Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000376

Drug Information
NameTolterodine
SynonymsMolPort-002-885-868; CID443879; 2-{(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl}-4-methylphenol; MLS001304745; CHEBI:9622; Jsp001637; AC1L9FDR; Tolterodina; FT-0082998; SMR000596518; AC-3472; NCGC00159519-02; 2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol; tolterodine; Kabi-2234; 2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-methylphenol; FT-0082150; Tolterodinum; MLS001195620; MolPort-005-934-224; BIDD:GT0318; CHEMBL1382; 124937-51-5; LS-187278; 2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
Trade NameDetrol; Detrusitol
CompanyPfizer Pharmaceuticals
IndicationUrinary incontinence
[ICD9: 788.3   ICD10: N39.3, N39.4, R32]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C22H31NO/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(
5)11-12-22(21)24/h6-12,15-17,20,24H,13-14H2,1-5H3/t20-/m1/s1
InChIKeyOOGJQPCLVADCPB-HXUWFJFHSA-N
Canonical SMILESCC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2    
Isomeric SMILESCC1=CC(=C(C=C1)O)[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2
Therapeutic ClassAntispasmodics
CAS NumberCAS 124937-51-5
FormulaC22H31NO
PubChem Compound IDCID 443879.
PubChem Substance IDSID 14777260.
ChEBI9622;
SuperDrug ATC IDG04BD07
SuperDrug CAS ID124937515;
TargetMuscarinic acetylcholine receptor M3Antagonist[2][3]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Signal transduction underlying carbachol-induced contraction of human urinary bladder. J Pharmacol Exp Ther. 2004 Jun;309(3):1148-53. Epub 2004 Feb 9. To Reference
Ref 3Nat Rev Drug Discov. 2003 Jan;2(1):38-51.Knockouts model the 100 best-selling drugs--will they model the next 100? To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543