Therapeutic Targets Database
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TTD Drug ID: DAP000413

Drug Information
NamePropericiazine
SynonymsC21H23N3OS; 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile; propericiazine(jan); 6909 RP; NCGC00095086-02; BRD-K89669299-001-02-7; HMS502L16; CID4747; 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine; Spectrum4_000210; CHEBI:31981; Periciazinum; NCGC00095086-03; KBio2_002094; IC 6002; Spectrum3_000748; Neuleptil; KBioSS_002094; Periciazine [INN]; Phenothiazine-2-carbonitrile, 10-(3-(4-hydroxypiperidino)propyl)-; Spectrum_001614; Piperocyanomazine; AC1Q4RQI; Nemactil; MolPort-003-981-163; Spectrum5_001747; SPBio_001607; Periciazinum [INN-Latin]; Periciazina; EINECS 220-071-3; Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine; DivK1c_000874; Spectrum2_001604; Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine [French]; Periciazina [INN-Spanish]; 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine; BRN 0576739; 2622-26-6; RP 8908; UNII-3405M6FD73; Neuleptil (TN); D01485; Aolept; KBio3_001556; KBio2_007230; Propericiazine (JAN); Bayer 1409; F.I. 6145; LS-105273; Propericiazine; Neulactil; KBio1_000874; 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile; WH 7508; SKF 20,716; KBioGR_000819; 4-Piperidinol, 1-(3-(2-cyano-10-phenothiazinyl)propyl)-; IDI1_000874; CHEMBL251940; AR-1L2302; DB01608; PERICYAZINE; periciazine; KBio2_004662; HMS1922M18; NINDS_000874; BSPBio_002336; 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile; SPECTRUM1503936; AC1L1IV8; NCGC00095086-01
Trade NameNeulactil
CompanySanofi-Aventis
IndicationPsychotic disorders
[ICD9: 290-299   ICD10: F20-F29]
Approved    [1]
Structure

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InChI1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21
)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2
InChIKeyLUALIOATIOESLM-UHFFFAOYSA-N
Canonical SMILESC1CN(CCC1O)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C#N    
Therapeutic ClassAntipsychotic Agents
CAS NumberCAS 2622-26-6
FormulaC21H23N3OS
PubChem Compound IDCID 4747.
PubChem Substance IDSID 160653.
ChEBI31981;
SuperDrug ATC IDN05AC01
SuperDrug CAS ID002622266;
TargetAlpha-1B adrenergic receptorBinder[2]
Ref 1Drug Information of Troleandomycin from NEXTBIO. To Reference
Ref 2Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action. Biol Psychiatry. 1984 Sep;19(9):1283-91. To Reference



 

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