Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000429

Drug Information
NameMelatonin
SynonymsNCGC00090727-02; CCRIS 3472; KBio3_002226; WLN: T56 BMJ D2MV1 GO1; A4039/0172195; NCGC00090727-03; NCGC00090727-06; KBio1_000353; HSCI1_000400; N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide; HSDB 7509; 5-22-12-00042 (Beilstein Handbook Reference); BIDD:ER0618; Melovine; Prestwick2_000458; PREVENTION 1 (MELATONIN) (PREVENTION 1); MolPort-000-737-883; D008550; NCGC00090727-07; EINECS 200-797-7; MLS001240204; AC1Q4F1X; Revital Melatonin; PREVENTION 2 (MELATONIN); Melatonin; NCGC00015680-13; D08170; ML1; AKOS000276269; HMS501B15; N-[2-(5-methoxyindol-3-yl)ethyl]acetamide; DivK1c_000353; SMR000326666; Circadin; KBioSS_000665; Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-; PREVENTION 3 (MELATONIN); Nature'S Harmony; Spectrum2_001344; NINDS_000353; M1105; AB00053279; BRD-K97530723-001-07-6; MLS000859594; KBio2_003233; NMR/14327425; Melatonex; SPBio_002475; SDCCGMLS-0065812.P002; Night Rest; CHEBI:16796; KBioGR_000591; N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide; EU-0100787; Melapure; AC1Q4F1W; Mela-T; CHEMBL45; NCGC00015680-01; BAS 01281092; NSC 113928; N-acetyl-5-methoxy-tryptamine; NCGC00090727-04; HMS1921E04; HMS1569K18; Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI); PREVENTION 5 (MELATONIN); SPECTRUM1500690; BRN 0205542; Prestwick_312; Melatonina; C01598; I10-0345; DB08189; 0E2B08C1-B325-45B1-8939-6F9081EFDFA4; SPBio_001527; NSC56423; NCGC00015680-06; KBio2_000665; Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-; M5250_SIGMA; PREVENTION 4 (MELATONIN); M-1200; Melatol; CID896; Posidorm; HMS1380B22; Bio-0635; Sleep Right; MLS001055382; Spectrum4_000066; L001261; Prestwick0_000458; S1204_Selleck; NCI60_004378; M-1250; ChemDiv2_003916; Oprea1_104553; NCGC00090727-09; NCGC00015680-02; DB01065; SMP2_000309; Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI); CAS-73-31-4; LS-1623; IDI1_002631; Melatonina (TN); KBio2_005801; Prestwick1_000458; Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-; N-Acetyl-5-methoxytryptamine; Rx Balance; Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-; STK386880; BPBio1_000590; MT6; Melatonine; Vivitas; N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide; NCGC00090727-05; Lopac0_000787; BSPBio_003006; Prestwick3_000458; IDI1_000353; Spectrum5_001745; NCGC00090727-01; NCGC00015680-03; I05-0076; Spectrum_000185; Oprea1_814234; ZINC00057060; HMS2089F09; Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI); Spectrum3_001393; BSPBio_000536; 73-31-4; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide; NCGC00090727-08; UNII-JL5DK93RCL; 4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID; Pineal Hormone; IN1244; Melatonex, Melatonin; AC1L1A9Q; SDCCGMLS-0065812.P001; NSC113928; M 5250; 5-Methoxy-N-acetyltryptamine; Lopac-M-5250; TNP00300; Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}; Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}; N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
IndicationInsomnia
[ICD9: 307.41, 307.42, 327.0, 780.51, 780.52   ICD10: F51.0, G47.0]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3
-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
InChIKeyDRLFMBDRBRZALE-UHFFFAOYSA-N
Canonical SMILESCC(=O)NCCC1=CNC2=C1C=C(C=C2)OC    
Therapeutic ClassCentral Nervous System Depressants
CAS NumberCAS 73-31-4
FormulaC13H16N2O2
PubChem Compound IDCID 896.
PubChem Substance IDSID 2961.
ChEBI16796;
SuperDrug ATC IDN05CH01
SuperDrug CAS ID000073314;
TargetMelatonin receptor type 1ABinder[2][3]
Ref 1Melatonin and melatonergic drugs on sleep: possible mechanisms of action. Int J Neurosci. 2009;119(6):821-46. To Reference
Ref 2The human MT1 melatonin receptor stimulates cAMP production in the human neuroblastoma cell line SH-SY5Y cells via a calcium-calmodulin signal transduction pathway. J Neuroendocrinol. 2005 Mar;17(3):170-8. To Reference
Ref 3Coexpression of MT1 and RORalpha1 melatonin receptors in the Syrian hamster Harderian gland. J Pineal Res. 2005 Aug;39(1):21-6. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543