Therapeutic Targets Database
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TTD Drug ID: DAP000508

Drug Information
NameMephenytoin
Synonyms3-Methyl-5-ethyl-5-phenylhydantoin; KBio2_004542; Mephenytoine; MLS002154157; Hydantoin, 5-ethyl-3-methyl-5-phenyl-; 5-Ethyl-5-fenyl-3-methylhydantoin [Czech]; (+-)-5-Ethyl-3-methyl-5-phenylhydantoin; BRD-A83937277-001-03-0; Prestwick1_001108; MolPort-003-666-498; NCGC00165924-01; Insulton; Sedantoinal; EINECS 200-012-8; 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione; 5 Ethyl 3 Methyl 5 Phenylhydantoin; Methyl hydantoin; Metydan; 5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione; 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (+-)-; Prestwick0_001108; NSC34652; BIM-0051837.0001; MEPHENYTOIN; 3-Methyl-5,5-ethylphenylhydantoin; Sacerno; HMS2089J22; Mesontoin; Oprea1_289074; KBioSS_001974; IDI1_000937; 3-Ethylnirvanol; 5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione; 2, 4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-; 3-Methyl-5, 5-ethylphenylhydantoin; 3-Methyl-5,5-phenylethylhydantoin; 3-Methyl-5-ethyl-5-phenylh; Fenantoin; CHEMBL861; WLN: T5MVNV EHJ C1 E2 ER; Triantoin; NIOSH/MU2276000; BRN 0017282; Epilan; NSC 34652; HMS1571M18; Phenetoin, Methyl; l-Mephenytoin; KBio2_001974; 5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione; 50-12-4; SMR001233457; AC-15964; Spectrum_001494; AB00052368; Mephenetoinum; HMS502O19; DB00532; KBio1_000937; NCGC00165924-02; Mephenytoine [INN-French]; Mephenytoinum; NINDS_000937; HSDB 3581; BSPBio_001216; Gerot-epilan; DivK1c_000937; Methyl Phenetoin; NSC-34652; 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-; AC1L1HBP; A1073/0050334; Mesantoin; LS-76189; Mephenytoinum [INN-Latin]; Mephenytoin (USP/INN); BPBio1_001338; (-)-5-Ethyl-3-methyl-5-phenylhydantoin; Mefenitoina; Phenantoin; 3-Methyl-5,5-phenylethylhydantoin; Methoin; mephentoin; KBio2_007110; Methylphenetoin; Mesantoin (TN); KBioGR_001508; SPBio_003088; 5-Ethyl-3-methyl-5-phenylhydantoin; Mesdontoin; 5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione; Prestwick2_001108; Sedantoin; (+-)-Mephenytoin; D00375; LS-76188; Spectrum4_001094; Sedantional; Mefenetoin; ydantoin; 5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione; 5-Ethyl-3-methyl-5-phenylhydantoin; 5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione; Hydantoin, 5-ethyl-3-methyl-5-phenyl-; Phenylethylmethylhydantoin; Epiazin; 5-Ethyl-5-fenyl-3-methylhydantoin; Mephenytoin [USAN:INN]; MU2276000; CID4060; l-3-Methyl-5-ethyl-5-phenylhydantoin; D008617; Prestwick3_001108; Mefenitoina [INN-Spanish]; Hydantoin, 5-ethyl-3-methyl-5-phenyl-, (-)-
Trade NameMesantoin
CompanyNorvatis Phamaceuticals Corporation
IndicationEpilepsy
[ICD9: 345   ICD10: G40]
Approved    [1]
Structure

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InChI1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,
3H2,1-2H3,(H,13,16)
InChIKeyGMHKMTDVRCWUDX-UHFFFAOYSA-N
Canonical SMILESCCC1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2    
Therapeutic ClassAnticonvulsants
CAS NumberCAS 50-12-4
FormulaC12H14N2O2
PubChem Compound IDCID 4060.
PubChem Substance IDSID 92176.
SuperDrug ATC IDN03AB04
SuperDrug CAS ID000050124;
TargetSodium channel protein type 5 subunit alphaBlocker[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 006008 To Reference
Ref 2Lacosamide: a new approach to target voltage-gated sodium currents in epileptic disorders. CNS Drugs. 2009;23(7):555-68. doi: 10.2165/00023210-200923070-00002. To Reference



 

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