Therapeutic Targets Database
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TTD Drug ID: DAP000519

Drug Information
NameEncainide
SynonymsEncainida; Encainide (INN); BRN 0497572; no stereochem; (.+/-.)-4-Methoxy-N-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]benzamide; LS-174678; AC1L2J99; 66778-36-7; (+-)-4-Methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide; BENZAMIDE, 4-METHOXY-N-(2-(2-(1-METHYL-2-PIPERIDINYL)ETHYL)PHENYL)-, (+-)-; MJ-9067; 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide; C06978; C22H28N2O2; Encainidum [Latin]; Encainidum; MJ-9067-1; LS-27116; MJ 9067; Encainida [Spanish]; Encainide [INN:BAN]; 4-methoxy-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide; 5-22-09-00511 (Beilstein Handbook Reference); Encainide; UNII-SY3J0147NB; 37612-13-8; (+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide; D07894; Encainide Hydrochloride, (+-)-Isomer; 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide; CHEBI:4788; Enkaid; Encainide [French]; AC1Q5EI5; CID48041
IndicationIrregular heartbeats
[ICD9: 427   ICD10: I47-I49]
Approved    [1]
Structure

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InChI1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(2
5)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,
16H2,1-2H3,(H,23,25)
InChIKeyPJWPNDMDCLXCOM-UHFFFAOYSA-N
Canonical SMILESCN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC    
Therapeutic ClassAnti-Arrhythmia Agents
CAS NumberCAS 66778-36-7
FormulaC22H28N2O2
PubChem Compound IDCID 48041.
PubChem Substance IDSID 9192.
SuperDrug ATC IDC01BC08
SuperDrug CAS ID066778367;
TargetSodium channel protein type 5 subunit alphaBlocker[2]
Ref 1New antiarrhythmic drugs: tocainide, mexiletine, flecainide, encainide, and amiodarone. Mayo Clin Proc. 1987 Nov;62(11):1033-50. To Reference
Ref 2From first class to third class: recent upheaval in antiarrhythmic therapy--lessons from clinical trials. Am J Cardiol. 1996 Aug 29;78(4A):28-33. To Reference



 

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