Therapeutic Targets Database
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TTD Drug ID: DAP000520

Drug Information
NameFosphenytoin
Synonyms3-(hydroxymethyl)phenytoin disodium phosphate; AC1Q6NQH; HMPDP; 2,4-imidazolidinedione, 5,5-diphenyl-3-[(phosphonooxy)methyl]-; Fosfenitoina [INN-Spanish]; ACC-9653; Fosphenytoin [INN:BAN]; LS-187339; D07993; C07840; Fosphenytoinum; Fosphenytoin; 2,4-Imidazolidinedione, 5,5-diphenyl-3-((phosphonooxy)methyl)-; (2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl dihydrogen phosphate; CID56339; Fosphenytoine [INN-French]; Fosphenytoin (INN); (3-Phosphoryloxymethyl)phenytoin; BIDD:GT0220; LS-178209; 93390-81-9; Fosphenytoinum [INN-Latin]; AC1L1KUO; DB01320; Fosphenytoine; UNII-B4SF212641; Fosfenitoina; 92134-98-0 (di-hydrochloride salt); Prodilantin; HSDB 7523; 3-(hydroxymethyl)phenytoin phosphate ester; 2,4-Imidazolidinedione, 5,5-diphenyl-3-((phosphonooxy)methyl)-, (SP-4-2)-
Trade NameCerebyx; Prodilantin
CompanyPfizer Pharmaceuticals
IndicationSeizures
[ICD9: 345.9, 780.3   ICD10: G40, P90, R56]
Approved    [1]
Structure

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InChI1S/C16H15N2O6P/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(2
0)18(14)11-24-25(21,22)23/h1-10H,11H2,(H,17,20)(H2,21,22,23)
InChIKeyXWLUWCNOOVRFPX-UHFFFAOYSA-N
Canonical SMILESC1=CC=C(C=C1)C2(C(=O)N(C(=O)N2)COP(=O)(O)O)C3=CC=CC=C3    
Therapeutic ClassAnticonvulsants
CAS NumberCAS 93390-81-9
FormulaC16H15N2O6P
PubChem Compound IDCID 56339.
PubChem Substance IDSID 10042.
SuperDrug ATC IDN03AB05
SuperDrug CAS ID093390819;
TargetSodium channel protein type 5 subunit alphaBlocker[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 076886 To Reference
Ref 2Lacosamide: a new approach to target voltage-gated sodium currents in epileptic disorders. CNS Drugs. 2009;23(7):555-68. doi: 10.2165/00023210-200923070-00002. To Reference



 

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