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TTD Drug ID: DAP000524

Drug Information
NameCandesartan
Synonyms2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid; CV11974; candesartan; D00522; 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-; Candesartan [USAN:INN]; UNII-S8Q36MD2XX; Candesartan (USAN/INN); S1578_Selleck; KS-5003; 2-ethoxy-7-carboxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylbenzimidazole; Candesartan [BAN]; I01-0374; AC-203; HSDB 7520; 139481-59-7; MolPort-005-943-739; FT-0083585; 2-(ethyloxy)-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid; CID2541; 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl}-1H-benzimidazole-7-carboxylic acid; Atacand, Blopress, Amias, Ratacand,Candesartan; CV 11974; CV-11974; CHEBI:216848; C081643; Blopress (TN); NCGC00167474-01; 2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylic acid; MolPort-003-845-570; CHEBI:3347; CHEMBL1016; LS-32740; C07468; 2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl] methyl]-3H-benzoimidazole-4-carboxylic acid; 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylic acid; C24H20N6O3; 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid; Blopress; 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid; TL8000897; AC1L1DWT; BIDD:GT0350; DB00796; L000156; 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-; HMS2089M22
Trade NameBlopress; Atacand; Amias; Ratacand
CompanyAstraZeneca
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-1
5-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,1
4H2,1H3,(H,31,32)(H,26,27,28,29)
InChIKeyHTQMVQVXFRQIKW-UHFFFAOYSA-N
Canonical SMILESCCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 139481-59-7
FormulaC24H20N6O3
PubChem Compound IDCID 2541.
PubChem Substance IDSID 9671.
ChEBI3347;
SuperDrug ATC IDC09CA06
SuperDrug CAS ID139481597;
TargetType-1 angiotensin II receptorAntagonist[2][3]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Candesartan: widening indications for this angiotensin II receptor blocker? Expert Opin Pharmacother. 2009 Aug;10(12):1995-2007. To Reference
Ref 3Angiotensin II type 1 receptor blockade: a novel therapeutic concept. Blood Press Suppl. 2000;1:9-13. To Reference



 

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