Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000574

Drug Information
NamePhendimetrazine
Synonyms(2S,3S)-3,4-Dimethyl-2-phenylmorpholine; Mephenmetrazine; DB01579; CID12460; NSC 169187; (+)-3,4-Dimethyl-2-phenylmorpholine; LS-92783; CID30487; 634-03-7; 16311-86-7; Morpholine, 3,4-dimethyl-2-phenyl-, (+)-; Fendimetrazina [INN-Spanish]; d-2-Phenyl-3,4-dimethylmorpholine; Phendimetrazine (INN); 21784-30-5; Wehless; CHEMBL1744; UNII-AB2794W8KV; hyrex; (2R-trans)-3,4-Dimethyl-2-phenylmorpholine; LS-173902; EINECS 211-204-6; 3-Phenyl-2-methylmorpholine; Adphen (base); Sedafamen; 3,4-Dimethyl-2-phenyltetrahydro-1,4-oxazine; AC1L1JNO; x-Trozine; phendimetrazine; D08347; Phendimetrazinum; Adphen; 17140-98-6 (hydrochloride); NSC169187; phendimetrazine, (2S-trans)-isomer; DEA No. 1615; Morpholine, 3,4-dimethyl-2-phenyl-, ( )-; 711-71-7; Morpholine, 3,4-dimethyl-2-phenyl-, (2S-trans)-; MolPort-000-003-187; (+)-Phendimetrazine; Phendimetrazinum [INN-Latin]; Morpholine, 3,4-dimethyl-2-phenyl-; Dyrexan; 3,4-Dimethyl-2-phenylmorpholine; Fendimetrazina; Antapentan; AC1L1ZN6; HSDB 3381; ZINC22010387; C07904; Phendimetrazine [INN:BAN]
Trade NameAdipost; Anorex-SR; Bontril PDM; Appecon; Bontril; Obezine; Phendiet; Plegine; Prelu-2; Statobex; Melfiat
IndicationObesity
[ICD9: 278   ICD10: E66]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C12H17NO/c1-10-12(14-9-8-13(10)2)11-6-4-3-5-7-11/h3-7,10,12H,8
-9H2,1-2H3/t10-,12+/m0/s1
InChIKeyMFOCDFTXLCYLKU-CMPLNLGQSA-N
Canonical SMILESCC1C(OCCN1C)C2=CC=CC=C2    
Isomeric SMILESC[C@H]1[C@@H](OCCN1C)C2=CC=CC=C2
Therapeutic ClassAnorexigenic Agents
CAS NumberCAS 634-03-7
FormulaC12H17NO
PubChem Compound IDCID 30487.
PubChem Substance IDSID 10106.
TargetAlpha-1B adrenergic receptorAntagonist[2]
Ref 1Anti-obesity drugs and neural circuits of feeding. Trends Pharmacol Sci. 2008 Apr;29(4):208-17. Epub 2008 Mar 18. To Reference
Ref 2Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543