Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000588

Drug Information
NameQuinapril
Synonyms(3S)-2-(N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; DivK1c_000710; quinapril; KBio2_002077; KBio2_004645; Spectrum_001597; Quinapril [INN:BAN]; NINDS_000710; 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, (3S-(2(R*(R*)),3R*))-; 85441-61-8; KBio3_002522; DB00881; AC1Q63IE; IDI1_000710; Quinaprilum; C07398; KBioGR_000994; Quinapril (USP/INN); CHEBI:8713; QUINAPRIL HCL; BSPBio_003022; Spectrum3_001551; Spectrum5_001075; BIDD:GT0797; (3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; C25H30N2O5; SPBio_000749; HMS2090L05; (3S)-2-{N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; UNII-RJ84Y44811; Spectrum2_000825; BRD-K72222507-003-03-6; HMS502D12; Spectrum4_000727; Quinaprilum [Latin]; NCGC00167962-01; MolPort-003-987-265; CHEMBL1592; CID54892; (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; KBio1_000710; [3S-[2[R*(R*)],3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-Isoquinolinecarboxylic acid ; Ectren; Koretic; Quinapril; NCGC00167962-02; D03752; KBioSS_002077; AB1004863; AC1L1HXL; LS-177872; TL8005458; KBio2_007213
Trade NameAccupril
CompanyPfizer Pharmaceuticals
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(
28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,
3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1
InChIKeyJSDRRTOADPPCHY-HSQYWUDLSA-N
Canonical SMILESCCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O    
Isomeric SMILESCCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 85441-61-8
FormulaC25H30N2O5
PubChem Compound IDCID 54892.
PubChem Substance IDSID 9602.
ChEBI8713;
SuperDrug ATC IDC09AA06
SuperDrug CAS ID085441618;
TargetAngiotensin-converting enzymeInhibitor[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2An experimental model of encapsulating peritoneal sclerosis. Perit Dial Int. 2009 Feb;29 Suppl 2:S49-50. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543