Therapeutic Targets Database
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TTD Drug ID: DAP000592

Drug Information
NameCarbidopa
SynonymsSMR000058235; Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, (S)-; S1891_Selleck; CHEBI:39585; Carbidopa (anhydrous); Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S); S-(-)-alpha-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid; MLS000069628; (S)-carbidopa hydrate; NCGC00024596-05; (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid; L-alpha-Methyldopahydrazine; Lodosyn; N-Aminomethyldopa; HMS2089B12; NCGC00024596-03; L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alpha-hydrazinopropionic acid; MLS002207014; CHEMBL1201236; 31823-41-3; NCGC00024596-01; Carbidopa Monohydrate; CPD-11550; Carbidopa, (S)-Isomer; Carbidopum [INN-Latin]; Atamet; Carbidopa-1-wasser; MolPort-003-940-629; HYDROCINNAMIC ACID, alpha-HYDRAZINO-3,4-DIHYDROXY-alpha-METHYL-, L-; Carbidopa [USAN:INN:BAN]; 27925-91-3; UNII-MNX7R8C5VO; (S)-carbidopa; CHEMBL1200748; CID38101; Lopac0_000382; 38821-49-7; L-alpha-Methyl-alpha-hydrazino-beta-(3,4-dihydroxyphenylpropionic acid; (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate; Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S)-; L-alpha-(3,4-dihydroxybenzyl)-alpha-hydrazinopropionic acid monohydrate; Carbidopa hydrate; EU-0100382; C1335_SIGMA; S(-)-CARBIDOPA; Methyldopahydrazine; CID34359; AC1L1Z32; MK 486; Lodosyn, Carbidopa; BB_SC-5095; MK-486; (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate; LS-77199; SMP1_000057; KINSON, 3-(3,4-DIHYDROXY-PHENYL)-2-HYDRAZINO-2-METHYL-PROPIONIC ACID; ST055523; CHEBI:3395; (S)-(-)-carbidopa; S-(-)-Carbidopa; S(-)-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate; C-DOPA; (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid--water (1/1); (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid; DB00190; alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid; L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid; (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid monohydrate; (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid; Carbidopa, Entacapone, & Levodopa; (S)-alpha--Hydrazino-3,4-dihydroxy-alpha--methyl-benzenepropanoic acid monohydrate; Carbidopum; AC1L1RFR; carbidopum monohydricum; carbidopa; 28860-95-9; Hadrazino-alpha-methyldopa; NCGC00024596-06; (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid; UNII-KR87B45RGH; AC-1676; Carbidopa anhydrous; MolPort-005-934-181; Stalevo; C126_SIGMA; AC1Q5QGW; Lodosin; C-126; Hydrocinnamic acid, (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate; (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate; CCRIS 5093; (S)-(-)-carbidopa hydrate; alpha-Methyldopahydrazine; MK-485; EINECS 249-271-9; Tocris-0455
Trade NameLodosyn
IndicationParkinson's disease
[ICD9: 332   ICD10: F02.3, G20]
Approved    [1]
Structure

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InChI1S/C10H14N2O4.H2O/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4
,12-14H,5,11H2,1H3,(H,15,16);1H2/t10-;/m0./s1
InChIKeyQTAOMKOIBXZKND-PPHPATTJSA-N
Canonical SMILESCC(CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.O    
Isomeric SMILESC[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.O
Therapeutic ClassAntiparkinson Agents
CAS NumberCAS 28860-95-9
FormulaC10H14N2O4
PubChem Compound IDCID 38101.
PubChem Substance IDSID 179362.
SuperDrug ATC IDN04BA03
TargetAromatic-L-amino-acid decarboxylaseInhibitor[2]
Ref 1Emerging drugs for restless legs syndrome. Expert Opin Emerg Drugs. 2005 Aug;10(3):537-52. To Reference
Ref 2Catechol-O-methyltransferase inhibitors in the management of Parkinson's disease. Semin Neurol. 2001;21(1):15-22. To Reference



 

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