Therapeutic Targets Database
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TTD Drug ID: DAP000593

Drug Information
NameDipivefrin
SynonymsLS-121419; 2,2-Dimethylpropanoic acid 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester; 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate; (+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate; Propine; dipivefrin; dipivalyl epinephrine; Prestwick0_000632; NCGC00179499-01; Dipivefrin (USAN); Dipivefrinum; UNII-8Q1PVL543G; ( -)-4-(1-Hydroxy-2-methylaminoethyl)-o-phenylendipivalat; 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate); AB00514686; Dipivefrina [INN-Spanish]; Prestwick1_000632; Ophtho-Dipivefrin; 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol; Dipivefrine; (RS)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylen dipivalat; AKOS003662293; K 30081; Dipivefrin HCL; CHEBI:4646; (+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol 3,4-dipivalate; C06963; Dipivefrina; BPBio1_000688; [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate; Dipivefrin [USAN]; C19H29NO5; AKPro; 52365-63-6; SPBio_002843; Dipivefrine (INN); Prestwick2_000632; Dipivefrinum [INN-Latin]; BRD-A47494775-003-03-0; DB00449; Propanoic acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ester, (+-)-; BSPBio_000624; ( -)-2,2-Dimethylpropansaeure-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylenester; AC1L1F6K; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylen dipivalat; Prestwick3_000632; D02349; CID3105; Propine C Cap B.I.D.; nchembio747-comp3; L000915
IndicationOpen-angle glaucoma
[ICD9: 365   ICD10: H40-H42]
Approved    [1]
Structure

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InChI1S/C19H29NO5/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)
25-17(23)19(4,5)6/h8-10,13,20-21H,11H2,1-7H3
InChIKeyOCUJLLGVOUDECM-UHFFFAOYSA-N
Canonical SMILESCC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C    
Therapeutic ClassOphthalmologicals
CAS NumberCAS 52365-63-6
FormulaC19H29NO5
PubChem Compound IDCID 3105.
PubChem Substance IDSID 9177.
SuperDrug ATC IDS01EA02
SuperDrug CAS ID052365636;
TargetBeta adrenergic receptorAntagonist[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 073636 To Reference
Ref 2Contractile response of the isolated trabecular meshwork and ciliary muscle to cholinergic and adrenergic agents. Ger J Ophthalmol. 1996 May;5(3):146-53. To Reference



 

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