Therapeutic Targets Database
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TTD Drug ID: DAP000653

Drug Information
NameLomefloxacin
SynonymsDB00978; TL8006033; UNII-9VC7S3ZXXB; SC-47111 (hydrochloride); SC 47111A; CHEMBL561; BSPBio_003107; BSPBio_000315; Lomefloxacinum [Latin]; SPBio_000851; 98079-52-8 (HYDROCHLORIDE); BRD-A75850590-003-05-6; 98079-51-7; 3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-; Prestwick2_000238; CID3948; Lomefloxacin (USAN); L2906_SIGMA; ST072201; BRN 4210041; NY-198 (hydrochloride); DM 10 (bactericide); Prestwick0_000238; 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; SC-4711; (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; KBio3_002607; lomefloxacin; SC-47111B (mesylate); NCGC00178293-02; Prestwick1_000238; Maxaquin (hydrochloride); KBio2_007047; Lomefloxacino [Spanish]; KBio2_004479; BPBio1_000347; SMP1_000287; D02318; CCRIS 6305; C17H19F2N3O3; DivK1c_000365; LS-141570; KBio2_001911; SC-47111A; 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride; Lopac0_000678; NCGC00178293-01; Spectrum3_001494; C07078; DM-10; Prestwick3_000238; 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; KBioSS_001911; NCGC00162221-01; 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo- (+/-); SC 4711; CHEBI:116278; Lomefloxacine; 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; Spectrum5_001246; Lomefloxacin [USAN:BAN:INN]; Lomefloxacino; IDI1_000365; Spectrum2_000696; AC1L1H2N; (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-; NCGC00015603-05; SPBio_002236; NINDS_000365; HMS2090O16; KBio1_000365; Spectrum4_000158; Lomefloxacine [French]; UNII-L6BR2WJD8V; KBioGR_000636; 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, (+-)-; Lomefloxacinum; Spectrum_001431; LFLX
Trade NameMaxaquin; Okacyn; Uniquin
IndicationBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
Approved    [1]
Structure

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InChI1S/C17H19F2N3O3/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)1
4(10)21)22-5-4-20-9(2)7-22/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25)
InChIKeyZEKZLJVOYLTDKK-UHFFFAOYSA-N
Canonical SMILESCCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O    
Therapeutic ClassAnti-Bacterial Agents
CAS NumberCAS 98079-51-7
FormulaC17H19F2N3O3
PubChem Compound IDCID 3948.
PubChem Substance IDSID 9289.
SuperDrug ATC IDJ01MA07; S01AE04
SuperDrug CAS ID098079517;
TargetDNA topoisomerase IIInhibitor[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020013 To Reference
Ref 2Inhibition of human topoisomerase IIalpha by fluoroquinolones and ultraviolet A irradiation. Toxicol Sci. 2002 Sep;69(1):16-22. To Reference



 

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