Therapeutic Targets Database
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TTD Drug ID: DAP000667

Drug Information
NameButabarbital
Synonyms125-40-6; Butrate; Unicelles; 5-SEC-BUTYL-5-ETHYL-BARBITURIC ACID; NSC 27517; BRN 0199734; 5-Ethyl-5-isobutylbarbituric acid; 1135-61-1; Secbutabarbital [INN]; LS-23930; NSC27517; BRN 0199127; 97164-73-3; Sodium butabarbital; 5-Sec-butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; Secbutabarbitalum; Butisol sodium; Butabarbital [USAN]; CHEBI:3228; Butabarbital (VAN); HSDB 3018; Secbutabarbitalum [INN-Latin]; Butatal; Butabarbital (USP); sec-Butobarbitone; 5-Ethyl-5-(1-methylpropyl)barbituric acid; 5-Ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-butan-2-yl-5-ethyl-1,3-diazinane-2,4,6-trione; Butatab; Nilox; Secbutabarbital; EINECS 204-738-6; MolPort-004-285-873; AC-16078; 5-Ethyl-5-(1-methylpropyl)barbiturate; D03180; 5-(butan-2-yl)-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione; UNII-P0078O25A9; Butabarb; Sarisol; Butabarbitone; Buticaps; Medarsed; WLN: T6VMVMV FHJ FY2 & 1 F2; Barbituric acid, 5-ethyl-5-isobutyl-; 5-sec-butyl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione; CHEMBL449; Secbutobarbital; Secbutobarbitone; C07827; Barbituric acid, 5-sec-butyl-5-ethyl-; CID2479; LS-24330; butabarbital; AC1L1DRT; DB00237; 5-sec-Butyl-5-ethylmalonyl urea; 5-ethyl-5-(1-methylpropyl)pyrimidine-2,4,6(1H,3H,5H)-trione; 5-sec-Butyl-5-ethylbarbituric acid; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylpropyl)-; Secbutabarbitale [DCIT]; Butalan; Secbubarbital; Butisol; Secbutabarbitale
Trade NameButisol
IndicationInsomnia
[ICD9: 307.41, 307.42, 327.0, 780.51, 780.52   ICD10: F51.0, G47.0]
Approved    [1]
Structure

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InChI1S/C10H16N2O3/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14/h6H,4-5H2,1
-3H3,(H2,11,12,13,14,15)
InChIKeyZRIHAIZYIMGOAB-UHFFFAOYSA-N
Canonical SMILESCCC(C)C1(C(=O)NC(=O)NC1=O)CC    
Therapeutic ClassAnti-anxiety Agents
CAS NumberCAS 125-40-6
FormulaC10H16N2O3
PubChem Compound IDCID 2479.
PubChem Substance IDSID 10029.
ChEBI3228;
TargetGamma-aminobutyric acid receptor subunit alpha-1Antagonist[2][3][4]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 085550 To Reference
Ref 2DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. To Reference
Ref 3Hypnotic drugs. Med Lett Drugs Ther. 2000 Aug 7;42(1084):71-2. To Reference
Ref 4Effect of barbiturates on polyphosphoinositide biosynthesis and protein kinase C activity in synaptosomes. Neuropharmacology. 1989 Dec;28(12):1317-23. To Reference



 

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