Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP000671

Drug Information
NamePentobarbital
SynonymsPentabarbitone; UNII-I4744080IR; DivK1c_000992; AC1L1IUE; D00499; Pentobarbitalum; Pentobarbital [USP:INN]; Spectrum5_001705; BSPBio_003305; 5-24-09-00168 (Beilstein Handbook Reference); Pentobarbital (USP/INN); Pentabarbital; Mebubarbital; Pentobarbital suppository dosage form; Pentobarbitale [DCIT]; Spectrum4_000574; HSDB 3151; Pentobarbitone; Etaminal; 5-Ethyl-5-(1-methylbutyl)malonylurea; (+-)-5-Ethyl-5-(1-methylbutyl)barbituric acid; KBio2_004834; KBio3_002807; Spectrum2_001991; CHEMBL448; 57-33-0 (mono-hydrochloride salt); Mebumal; KBioSS_002267; Neodorm (new); Oprea1_143902; Pentobarbital (VAN); Spectrum3_001783; Pentobarbiturate; KBio2_007402; HMS2094E21; LS-24385; SPECTRUM1900006; Ethaminal; Pentobarbitale; NINDS_000992; WLN: T6VMVMV FHJ FY3&1 F2; 5-ethyl-5-(pentan-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione; 5-Ethyl-5-(sec-pentyl)barbituric acid; NCGC00096074-01; MolPort-001-785-697; CCRIS 7089; SPBio_002201; C07422; 76-74-4; KBioGR_001008; Barbituric acid, 5-ethyl-5-(1-methylbutyl)-; CHEBI:7983; Nebralin; DEA No. 2270; Nembutal (TN); 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-, (+-)-; Pentobarbitalum [INN-Latin]; Neodorm; 5-Ethyl-5-(1-methylbutyl)barbituric acid; Spectrum_001783; 5-ethyl-2-hydroxy-5-(1-methylbutyl)pyrimidine-4,6(1H,5H)-dione; IDI1_000992; Nembutal (VAN); AKOS000277861; Aethaminalum; MolPort-003-666-760; NSC 28708; KBio1_000992; Dorsital; HMS503G05; 5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione; Pentobarbital calcium; Ethyl-propylmethylcarbinylbarbituric acid; Pentobarbituric acid; DB00312; Neodorm (VAN); Rivadorm; EINECS 200-983-8; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-; Pentobarbital, Monosodium Salt; BRN 0087067; pentobarbital; KBio2_002266; AC1Q2UJM; Barbituric acid, 5-ethyl-5-(2-pentyl)-; NCGC00096074-02; Oprea1_775730; CID4737; 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; Pentobarbitone (VAN); NSC28708; Nembutal
Trade NameNembutal
IndicationInsomnia
[ICD9: 307.41, 307.42, 327.0, 780.51, 780.52   ICD10: F51.0, G47.0]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H
2,1-3H3,(H2,12,13,14,15,16)
InChIKeyWEXRUCMBJFQVBZ-UHFFFAOYSA-N
Canonical SMILESCCCC(C)C1(C(=O)NC(=O)NC1=O)CC    
Therapeutic ClassHypnotics and Sedatives
CAS NumberCAS 76-74-4
FormulaC11H18N2O3
PubChem Compound IDCID 4737.
PubChem Substance IDSID 9626.
ChEBI7983;
SuperDrug ATC IDN05CA01
SuperDrug CAS ID000076744;
TargetGamma-aminobutyric acid receptor subunit alpha-1Antagonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 083270 To Reference
Ref 2DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. To Reference
Ref 3Effect of barbiturates on polyphosphoinositide biosynthesis and protein kinase C activity in synaptosomes. Neuropharmacology. 1989 Dec;28(12):1317-23. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543