Therapeutic Targets Database
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TTD Drug ID: DAP000683

Drug Information
NameMethyprylon
SynonymsCHEMBL1200790; 125-64-4; Ro 1-6463; Methprylon; 2,4-Dioxy-3,3-diethyl-5-methylpiperidine; HSDB 3128; methyprylon; AC1L1HJV; Dimerin; Methyprylon (JAN/INN); Nodular; Metiprilone; D01150; LS-115204; BRN 0082860; NSC 30442; CID4162; DB01107; C10H17NO2; 2,4-Piperidinedione, 3,3-diethyl-5-methyl-; Metiprilona [INN-Spanish]; Metiprilona; Methyprylon [INN]; UNII-CUT48I42ON; Noludar; Methyprylone [INN-French]; Methyprylonum; Methyprolon; Noludar (TN); 3,3-Diethyl-5-methylpiperidine-2,4-dione; MolPort-001-783-609; WLN: T6MV DVTJ C2 C2 E1; Methyprylonum [INN-Latin]; DEA No. 2575; NSC30442; EINECS 204-745-4; 2,4-Dioxo-3,3-diethyl-5-methylpiperidine; Methyprylone; 3,3-Diethyl-2,4-dioxo-5-methylpiperidine; Metiprilon; Noctan; 3,3-Diethyl-5-methyl-2,4-piperidinedione
IndicationInsomnia
[ICD9: 307.41, 307.42, 327.0, 780.51, 780.52   ICD10: F51.0, G47.0]
Approved    [1]
Structure

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InChI1S/C10H17NO2/c1-4-10(5-2)8(12)7(3)6-11-9(10)13/h7H,4-6H2,1-3H3,(H
,11,13)
InChIKeySIDLZWOQUZRBRU-UHFFFAOYSA-N
Canonical SMILESCCC1(C(=O)C(CNC1=O)C)CC    
Therapeutic ClassSedatives and Hypnotics
CAS NumberCAS 125-64-4
FormulaC10H17NO2
PubChem Compound IDCID 4162.
PubChem Substance IDSID 89654.
SuperDrug ATC IDN05CE02
SuperDrug CAS ID000125644;
TargetGamma-aminobutyric acid receptor subunit alpha-1Antagonist[2]
Ref 1Nonlinear elimination of methyprylon (noludar) in an overdosed patient: correlation of clinical effects with plasma concentration. J Pharm Sci. 1991 Aug;80(8):768-71. To Reference
Ref 2DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. To Reference



 

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