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TTD Drug ID: DAP000825

Drug Information
NameQuinacrine
SynonymsAcridine, 6-chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxy-; 83-89-6 (Parent); NCI60_000926; AC1NS008; Pentilen; acrichine; Erion; Haffkinine; GNF-PF-5448; CID149640; N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine monoacetate; DB01103; AC1L3ZIX; Spectrum4_000496; RP-866 (Dihydrochloride dihydrate); acetic acid; N'-(6-chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine; Italchin; BPBio1_000348; KBio1_000101; 866 R.P.; chinacrin; Mepacrina; BRD-A45889380-336-03-4; NSC14229; Quinacrine dihydrochloride dihydrate; NINDS_000101; 316-05-2 (dimesylate); AC1MBFYF; quinacrine; C23H30ClN3O.2HCl.2H2O; 2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine; KBioGR_001011; EINECS 201-508-7; Spectrum5_001405; Quinacrine dihydrochloride mustard; MolPort-004-285-521; AC1L18SD; Arichin; Prestwick1_000318; EINECS 204-989-1; Metochin; Mepacrine (INN); Spectrum2_000888; BSPBio_000316; IDI1_000101; CHEBI:8711; MS-1557; KBio2_002507; NCGC00180969-01; TCMDC-125480; Quinacrine Dihydrochloride, Dihydrate; nchembio.215-comp6; MolPort-001-739-072; STL061087; Mepacrinum [INN-Latin]; CCRIS 8633; Mepacrina [INN-Spanish]; Acrinamine; KBioSS_001409; N~4~-[6-chloro-2-(methyloxy)acridin-9-yl]-N~1~,N~1~-diethylpentane-1,4-diamine; D08179; CID2725002; Mepacrinum; AC1Q2BPT; SPBio_000676; Methoquine; BSPBio_002112; LS-190025; 3-Chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine; AB00053540; Quinactine; HMS2090L03; N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine; Spectrum3_000606; KBio2_006545; BAS 00439963; Prestwick3_000318; Acirchine; KBio3_001612; Acridine, 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy-; 6151-30-0; Prestwick2_000318; St 439; N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine; 130-42-7 (mono-hydrochloride); Atabrine dihydrochloride; 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-; Italchine; mepacrine; 78901-94-7 (monoacetate); AI3-04467; SPBio_002535; Mepacrine hydrochloride dihydrate; Atebrine; acetic acid; 4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine; RP 866; Spectrum_000929; 69-05-6; Palusan; 4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine; N~4~-(6-chloro-2-methoxyacridin-9-yl)-N~1~,N~1~-diethylpentane-1,4-diamine; Erion Hydrochloride; Mepacrine [INN:BAN]; AKOS000541535; Malaricida; Prestwick0_000318; Quinacrin; N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine; C07339; atebrin; NCGC00015874-04; KBio2_005075; KBio3_002985; LS-14294; HMS1568P18; 69-05-6 (di-hydrochloride); Prestwick_650; SAM001247040; CHEMBL7568; KBio2_001409; DivK1c_000101; Mecryl; KBioGR_002507; 130-42-7; SN-390 (Dihydrochloride dihydrate); CHEMBL546257; 6151-30-0 (di-hydrochloride, di-hydrate); KBio2_007643; NCGC00180899-01; atabrine; Lopac0_000970; CID5351141; 78901-94-7; Quinacrine acetate; Palacrin; KBioSS_002515; 83-89-6; Quinacrine hydrochloride dihydrate; Acriquine; cMAP_000067; KBio2_003977; AKOS004910405; HSDB 3253; Akrichin; Atabrine hydrochloride; CPD000449289; CID237; nchembio873-comp30; 6-Chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine; NCGC00162300-01; LS-14293; MLS000758289; Atabrine hydrochloride dihydrate; Antimalarina; WLN: T C666 BNJ EG IMY1&3N2&2 LO1 &GH 2; Mepacrine HCl; SMR000449289
Trade NameAtabrine
IndicationGiardiasis and cutaneous leishmaniasis
[ICD9: 007.1, 085.1-085.4   ICD10: A07.1, B55.1]
Approved    [1]
Structure

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InChI1S/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(
19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H
,25,26)
InChIKeyGPKJTRJOBQGKQK-UHFFFAOYSA-N
Canonical SMILESCCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC    
Therapeutic ClassAntihelmintics
CAS NumberCAS 83-89-6
FormulaC23H30ClN3O
PubChem Compound IDCID 237.
PubChem Substance IDSID 9546.
ChEBI8711;
SuperDrug ATC IDG01AD02; P01AX05; S02AA10
SuperDrug CAS ID000083896;
TargetPhospholipase A2Inhibitor[2]
Ref 1An FDA phase I clinical trial of quinacrine sterilization (QS). Int J Gynaecol Obstet. 2003 Oct;83 Suppl 2:S45-9. To Reference
Ref 2Involvement of protein kinase C activation in L-leucine-induced stimulation of protein synthesis in l6 myotubes. Cytotechnology. 2003 Nov;43(1-3):97-103. To Reference



 

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