Therapeutic Targets Database
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TTD Drug ID: DAP000907

Drug Information
NameOlmesartan
SynonymsD05246; C437965; Olmesartan (USAN/INN); RNH-6270; CS-088; 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid; MLS000759446; SMR000466337; 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid; CID158781; CHEBI:48416; MolPort-003-666-606; HMS2051K12; CPD000466337; SAM001246634; 144689-24-7; UNII-8W1IQP3U10; CHEMBL1516; LS-181800; Olmesartan [USAN]; L001097; 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-; MLS001424016; 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid; RNH 6270; 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid; Olmesartan; 4-(hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid; 4-(hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid; I14-10085; omesartan; AC1L4KLS
Trade NameBenicar; Olmetec
CompanyDaiichi Sankyo Pharma Development
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-1
0-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H
,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
InChIKeyVTRAEEWXHOVJFV-UHFFFAOYSA-N
Canonical SMILESCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)C(C)(C)O    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 144689-63-4
FormulaC29H30N6O6
PubChem Compound IDCID 158781.
PubChem Substance IDSID 736224.
ChEBI48416;
SuperDrug ATC IDC09CA08
SuperDrug CAS ID144689634;
TargetAngiotensin II receptor 1Antagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2A case of Henoch-Sch?nlein purpura nephritis successfully treated with tonsillectomy and steroid pulse therapy. Nippon Jinzo Gakkai Shi. 2009;51(4):484-9. To Reference



 

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