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TTD Drug ID: DAP000930

Drug Information
NameEstazolam
SynonymsEstazolam (JP15/USAN/INN); DB01215; Julodin; 8-Chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; BIDD:GT0481; LS-7378; Takeda Brand of Estazolam; BRN 1220868; ProSom; CID3261; AKOS005064373; Abbott Brand of Estazolam; Prosom (TN); Tasedan; Estazolam [USAN:INN:JAN]; I06-0352; DEA No. 2756; AC1L1FJ8; 4H-s-Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-6-phenyl-; Eurodin; Somnatrol; InChI=1/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2; 4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine, 8-chloro-6-phenyl-; D004949; Estazolamum [INN-Latin]; D00311; UNII-36S3EQV54C; ZINC00001370; 8-Chloro-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine; MolPort-003-941-274; CHEMBL285674; D40TA; CCRIS 1955; E3638_SIGMA; C16H11ClN4; U 33737; D-40TA; Hormona Brand of Estazolam; 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-6-phenyl-; D 40TA; estazolam; Nuctalon; 8-Chloro-6-phenyl-4H-(1,2,4)triazolo-(4,3-a)(1,4)benzodiazepine; NSC290818; Estazolamum; 8-chloro-6-phenyl-4H-s-triazolo[4,3-(alpha)] [1,4]benzodiazepine; CDCHDCWJMGXXRH-UHFFFAOYSA-; 4H-s-Triazolo[4,3-a][1,4]benzodiazepine, 8-chloro-6-phenyl-; 29975-16-4; NCGC00168250-01; CHEBI:4858; NSC 290818; Abbott 47631; Esilgan; 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-6-phenyl; EINECS 249-982-4; Nemurel; WLN: T B576 BN DNN HN GHJ IR& LG; 8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine (IUPAC); Cannoc
Trade NameProSom; Eurodin
IndicationInsomnia
[ICD9: 307.41, 307.42, 327.0, 780.51, 780.52   ICD10: F51.0, G47.0]
Approved    [1]
Structure

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InChI1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20
-19-10-21(14)15/h1-8,10H,9H2
InChIKeyCDCHDCWJMGXXRH-UHFFFAOYSA-N
Canonical SMILESC1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4    
Therapeutic ClassAnticonvulsants
CAS NumberCAS 29975-16-4
FormulaC16H11ClN4
PubChem Compound IDCID 3261.
PubChem Substance IDSID 145301.
SuperDrug ATC IDN05CD04
SuperDrug CAS ID029975164;
TargetBenzodiazepine receptorAgonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074818 To Reference
Ref 2Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3126-9. To Reference
Ref 3Design and synthesis of 4H-3-(2-phenoxy)phenyl-1,2,4-triazole derivatives as benzodiazepine receptor agonists. Bioorg Med Chem. 2003 Mar 6;11(5):769-73. To Reference



 

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