Therapeutic Targets Database
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TTD Drug ID: DAP001000

Drug Information
NameEnoxacin
SynonymsNINDS_000420; LS-95946; E3764_SIGMA; Bactidan; Spectrum2_001731; 74011-58-8; Enoxin; Faulding Brand of Enoxacin; NCGC00178309-02; 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-; Flumark; AT-2266; IDI1_000420; PD-107779; BPBio1_000491; HMS1569G07; C15H17FN4O3; Pierre Fabre Brand of Enoxacin Sesquihydrate; KBio2_007155; KBioGR_000651; 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; CL23362; PD 107779; Enoxacine [French]; HMS2090E10; Enoram; NSC 627409; BRN 3628995; E3764_FLUKA; BIDD:GT0191; BSPBio_003080; AC1L1FGQ; CI 919; Spectrum3_001570; SPECTRUM1503215; CAS-74011-58-8; CI-919; NCGC00178309-01; Enoxacin Sesquihydrate; enoxacin; Prestwick2_000353; NSC629661; KBio3_002580; BCBcMAP01_000009; BRD-K78113049-001-05-5; CHEBI:157175; I06-0290; Enoxacino [Spanish]; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid; AT 2266; NCGC00016927-01; CHEMBL826; Sesquihydrate, Enoxacin; CCRIS 5242; C06979; Prestwick1_000353; HMS2092N20; NCI60_009618; 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; Prestwick0_000353; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; Comprecin; SPBio_001802; Almitil; CID3229; Enoxor; NCGC00023864-04; KBioSS_002019; Enoxacin [USAN:BAN:INN:JAN]; E0762; SPBio_002366; D00310; BSPBio_000445; DivK1c_000420; HMS1922I17; Penetrex (TN); KBio2_004587; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7- [1-piperazinyl]-1,8-naphthyridine-3-carboxylic acid; HMS501E22; NSC 629661; UNII-325OGW249P; Enoxacin (USAN/INN); KBio2_002019; D015365; Spectrum4_000166; Enoxacinum; NCGC00023864-03; AT2266; CI919; KBio1_000420; DB00467; SMR000058233; 1,8-Naphthyridine-3-carboxylic acid, 6-fluoro-1,4-dihydro- 4-oxo-7-piperazinyl; Rhone-Poulenc Rorer Brand of Enoxacin Sesquihydrate; Prestwick_708; Enoxacino; Spectrum_001539; NCGC00016927-02; 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-; Oprea1_147866; Enoxacinum [Latin]; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid; SMP1_000113; Spectrum5_001044; PD107779; MLS000069645; Penetrex; Enoxacine; TL8005116; Prestwick3_000353; Rhone Poulenc Rorer Brand of Enoxacin Sesquihydrate
Trade NameAlmitil; Bactidan; Bactidron; Comprecin; Enoksetin; Enoxen; Enroxil; Enoxin; Enoxor; Flumark; Penetrex; Gyramid; Vinone
IndicationBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
Approved    [1]
Structure

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InChI1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)1
9)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)
InChIKeyIDYZIJYBMGIQMJ-UHFFFAOYSA-N
Canonical SMILESCCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O    
Therapeutic ClassAntiinfective Agents
CAS NumberCAS 74011-58-8
FormulaC15H17FN4O3
PubChem Compound IDCID 3229.
PubChem Substance IDSID 9193.
SuperDrug ATC IDJ01MA04
SuperDrug CAS ID074011588;
TargetDNA gyraseInhibitor[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019616 To Reference
Ref 2Clinical pharmacokinetics of the newer antibacterial 4-quinolones. Clin Pharmacokinet. 1988 Feb;14(2):96-121. To Reference



 

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