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TTD Drug ID: DAP001017

Drug Information
NameDanazol
SynonymsSMR000058321; SPBio_002029; 17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol; (1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol; CPD000058321; BRD-K48970916-001-03-0; ratiopharm Brand of Danazol; Danocrine (TN); Danogen; Sanofi Winthrop Brand of Danazol; WIN 17757; HMS2090A22; AC1L1FAD; LS-118524; AC-6836; NCGC00179665-01; 17-alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol; Danatrol; Danazant; EINECS 241-270-1; BSPBio_000090; Sanofi Synthelabo Brand of Danazol; Danazolum [INN-Latin]; WIN 17,757; AC1Q29FD; Winobanin; 20-yno[2,3-d]isoxazol-17-ol,} (17.alpha.)-; Prestwick3_000105; [1,2]oxazolo[4',5':2,3]-17alpha-pregn-4-en-20-yn-17-ol; Cyclomen; (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5,9-trien-17-ol; Chronogyn; Danol; D00289; Win 17, 757; Alphapharm Brand of Danazol; CID28417; UNII-N29QWW3BUO; BPBio1_000100; Danazol [USAN:BAN:INN:JAN]; CCRIS 6747; MolPort-002-513-504; Prestwick0_000105; anatrol; Danokrin; danazol; Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,(17alpha)-; Prestwick2_000105; CHEBI:4315; STOCK1N-23495; Danocrine; NCGC00164400-01; D003613; NSC270916; 1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol; 17.Alpha.-Pregna-2, {4-dien-20-yno[2,3-d]isoxazol-17-ol}; Pregna-2, {4-dien-; Danoval; Panacrine; MLS001066617; Kendrick Brand of Danazol; Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol, (17alpha)-; MLS001306473; 17230-88-5; Ladogal; Danazol-ratiopharm; 17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol; DB01406; Sanofi Brand of Danazol; NSC 270916; Antigen Brand of Danazol; Danazol (JAN/USP/INN); CHEMBL1479; Prestwick1_000105; Danazolum; WIN-17757; 17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol; SAM002564203; ZINC03881958; Danazole; Prestwick_150; Danzol; HMS1568E12; AC1Q282K; Norciden
Trade NameDanocrine
IndicationMenorrhagia
[ICD9: 627.0   ICD10: N92.0]
Approved    [1]
Structure

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InChI1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12
-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/
t16-,17+,18+,20+,21+,22+/m1/s1
InChIKeyPOZRVZJJTULAOH-LHZXLZLDSA-N
Canonical SMILESCC12CCC3C(C1CCC2(C#C)O)CCC4=CC5=C(CC34C)C=NO5    
Isomeric SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5
Therapeutic ClassFertility Agents
CAS NumberCAS 17230-88-5
FormulaC22H27NO2
PubChem Compound IDCID 28417.
PubChem Substance IDSID 170876.
ChEBI4315;
SuperDrug ATC IDG03XA01
SuperDrug CAS ID017230885;
TargetEstrogen receptorAntagonist[2]
Ref 1Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54. To Reference
Ref 2Danazol suppression of luteinizing hormone in the rat: evidence for mediation by both androgen and estrogen receptors. Proc Soc Exp Biol Med. 1990 May;194(1):54-7. To Reference



 

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