Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP001065

Drug Information
NameTriprolidine
SynonymsSpectrum5_001467; HSDB 6316; Histafed; LS-1293; BIDD:GT0569; UNII-YAN7R5L890; Myidyl; 6138-79-0 (mono-hydrochloride, mono-hydrate); Pro-Actidil; 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine chloride; Triprolidine Monohydrochloride; CHEBI:165539; Lopac0_001130; CID6433473; L000901; Actidilat; AC1NR02Y; CHEMBL855; 295 C 51; CCRIS 7215; MLS002207213; MLS000028751; FT-0082802; Triprolidine (INN); NCGC00024714-04; BSPBio_000104; IDI1_000297; Pyridine, 2-((1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, monohydrochloride; NCGC00024714-06; C19H22N2.HCl; Pyridine, 2-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, monohydrochloride, monohydrate, (E)-; 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine; CID5282443; MLS001148254; Prestwick2_000262; trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene; BSPBio_002255; HMS2089M21; AC-15905; HMS1921I07; Tripolidina [INN-Spanish]; 550-70-9; Triprolidine HCL; SMR000058521; 550-70-9 (mono-hydrochloride); Triprolidinum [INN-Latin]; Tripolidina; Triprolidine [INN:BAN]; 486-12-4; trans-2-(3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)pyridine; Triprolidine hydrochloride; EINECS 208-985-0; CCRIS 7212; EU-0101130; trans-1-(2-Pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene; HMS1568F06; Pro-Entra; CID5702129; Triprolidinum; NCGC00024714-03; EINECS 207-627-0; UNII-2L8T9S52QM; Entra; 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine hydrochloride; AC1NWAR4; DB00427; Pyridine, 2-((1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl)-, hydrochloride (1:1); Prestwick3_000262; BRD-K11742128-003-05-1; SPECTRUM1500598; NCI-C61450; (E)-2-(1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine; NCGC00094397-01; Pyridine, 2-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, monohydrochloride, (E)-; BPBio1_000116; CHEMBL1200450; BIM-0025383.P001; LS-131942; Actidil; AC1O5G9Y; Triprolidine Monohydrochloride, Monohydrate; Triprolidine hydrochloride anhydrous; NCGC00094397-02; T 6764; Triprolidine Hydrochloride (anhydrous); 486-12-4 (Parent); MolPort-003-182-178; trans-2-(3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)pyridine monohydrochloride; Pyridine, 2-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, (E)-; NCGC00094397-03; Triprolidin; MLS002222226; Venen (TN); Prestwick_575; C19H22N2; NCGC00024714-05; Venen; (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride; Pyridine, 2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)-, monohydrochloride, monohydrate, stereoisomer; D08648; 6138-79-0; Pyridine, 2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)-, monohydrochloride, (E)-; Pyridine, 2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)-, (E)-; MolPort-003-666-303; NCGC00024714-02; triprolidine
Trade NameActidil; Myidil; Actifed
IndicationHay fever
[ICD9: 477   ICD10: J30]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-2
1-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;
InChIKeyWYUYEJNGHIOFOC-NWBUNABESA-N
Canonical SMILESCC1=CC=C(C=C1)C(=CC[NH+]2CCCC2)C3=CC=CC=N3.[Cl-]    
Isomeric SMILESCC1=CC=C(C=C1)/C(=C\C[NH+]2CCCC2)/C3=CC=CC=N3.[Cl-]
Therapeutic ClassAntiallergic Agents
CAS NumberCAS 486-12-4
FormulaC19H22N2
PubChem Compound IDCID 6433473.
PubChem Substance IDSID 165169.
SuperDrug ATC IDR06AX07
SuperDrug CAS ID000486124;
TargetHistamine H1 receptorAntagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors. Neurosci Lett. 2008 Dec 19;448(1):15-9. Epub 2008 Oct 14. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543