Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DAP001131

Drug Information
NameDarifenacin
SynonymsNCGC00168775-01; DB00496; CID444031; STOCK6S-73577; Darifenacin; D03654; CHEBI:391960; MolPort-005-943-011; (S)-1-(2-(2,3-Dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide; 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide; Emselex; 2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide; AC1L9FKY; Darifenacin (USAN/INN); LS-187359; CHEMBL1346; AC-302; 133099-04-4
Trade NameEnablex; Emselex
CompanyNorvatis Phamaceuticals Corporation
IndicationUrinary incontinence
[ICD9: 788.3   ICD10: N39.3, N39.4, R32]
Approved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14
-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,
13-18,20H2,(H2,29,31)/t25-/m1/s1
InChIKeyHXGBXQDTNZMWGS-RUZDIDTESA-N
Canonical SMILESC1CN(CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5    
Isomeric SMILESC1CN(C[C@@H]1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5
Therapeutic ClassUrinary antispasmodics
CAS NumberCAS 133099-04-4
FormulaC28H30N2O2
PubChem Compound IDCID 444031.
PubChem Substance IDSID 7979027.
SuperDrug ATC IDG04BD10
G04BD10
TargetMuscarinic acetylcholine receptor M3Antagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2M(1) and M(3) muscarinic receptors are involved in the release of urinary bladder-derived relaxant factor. Pharmacol Res. 2009 May;59(5):300-5. Epub 2009 Feb 5. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543