Therapeutic Targets Database
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TTD Drug ID: DAP001253

Drug Information
NameMethsuximide
SynonymsN-Methyl-alpha-methyl-alpha-phenylsuccinimide; Mesuximidum [INN-Latin]; 1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione; DB05246; UNII-0G76K8X6C0; alpha-Methylphensuximide; 2,5-Pyrrolidinedione,1,3-dimethyl-3-phenyl-, (+-)-; 2,5-Pyrrolidinedione,1,3-dimethyl-3-phenyl-; (+-)-N,2-Dimethyl-2-phenylsuccinimide; 1,3-Dimethyl-3-phenylsuccinimide; Mesuximidum; BRN 0168315; alpha-Methyl-alpha-phenyl N-methyl succinimide; MolPort-003-666-689; 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione; PM 396; LS-147580; AC1Q3XU0; 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione; CID6476; AC1L1MM3; Metosuccimmide; Methsuximid; Mesuximide (INN); Metosuccimmide [DCIT]; C12H13NO2; AC-15963; mesuximid; METHSUXIMIDE; Mesuximide; HSDB 3124; Mesuximida [INN-Spanish]; Methsuximide [BAN]; Celontin; (RS)-1,3-Dimethyl-3-phenyl-2,5-pyrrolidindion; Celontin (TN); 5-21-11-00209 (Beilstein Handbook Reference); Mesuximida; 77-41-8; Methsuximide (USP); Petinutin; D00404; CHEMBL697; 2,5-Pyrrolidinedione, 1,3-dimethyl-3-phenyl-; EINECS 201-026-7; Succinimide, N,2-dimethyl-2-phenyl-; 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine; Metsuccimide; N,2-Dimethyl-2-phenylsuccinimide
Trade NamePetinutin; Celontin
CompanyPfizer Pharmaceuticals
IndicationEpileptic seizures
[ICD9: 345.9, 780.3   ICD10: G40, P90, R56]
Approved    [1]
Structure

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InChI1S/C12H13NO2/c1-12(9-6-4-3-5-7-9)8-10(14)13(2)11(12)15/h3-7H,8H2,
1-2H3
InChIKeyAJXPJJZHWIXJCJ-UHFFFAOYSA-N
Canonical SMILESCC1(CC(=O)N(C1=O)C)C2=CC=CC=C2    
Therapeutic ClassAnticonvulsants
CAS NumberCAS 77-41-8
FormulaC12H13NO2
PubChem Compound IDCID 6476.
PubChem Substance IDSID 149439.
SuperDrug ATC IDN03AD03
SuperDrug CAS ID000077418;
TargetVoltage-dependent T-type calcium channelBlocker[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 010596 To Reference
Ref 2Block of cloned human T-type calcium channels by succinimide antiepileptic drugs. Mol Pharmacol. 2001 Nov;60(5):1121-32. To Reference



 

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