Therapeutic Targets Database
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TTD Drug ID: DAP001256

Drug Information
NameForasartan
SynonymsUNII-065F7WPT0B; Forasartan; 5-[(3,5-dibutyl-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine; Pyridine, 5-((3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-yl)phenyl)-; L007541; AC1L31G8; DB01342; 145216-43-9; Forasartan (USAN/INN); SC-52458; CHEBI:239233; 5-((3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-ylphenyl))pyridine; D04243; SC 52458; CHEMBL315021; CID132706
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C23H28N8/c1-3-5-11-21-25-22(12-6-4-2)31(28-21)16-17-13-14-20(2
4-15-17)18-9-7-8-10-19(18)23-26-29-30-27-23/h7-10,13-15H,3-6,11-1
2,16H2,1-2H3,(H,26,27,29,30)
InChIKeyYONOBYIBNBCDSJ-UHFFFAOYSA-N
Canonical SMILESCCCCC1=NN(C(=N1)CCCC)CC2=CN=C(C=C2)C3=CC=CC=C3C4=NNN=N4    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 145216-43-9
FormulaC23H28N8
PubChem Compound IDCID 132706.
PubChem Substance IDSID 709018.
SuperDrug ATC IDC09CA
TargetType-1 angiotensin II receptorAntagonist[1][2]
Ref 1Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification. J Med Chem. 2003 Feb 27;46(5):716-26. To Reference
Ref 2Possible involvement of calcium-calmodulin pathways in the positive chronotropic response to angiotensin II on the canine cardiac sympathetic ganglia. Jpn J Pharmacol. 2001 Aug;86(4):381-9. To Reference



 

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