Therapeutic Targets Database
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TTD Drug ID: DAP001258

Drug Information
NameTasosartan
SynonymsCID60919; DB01349, Tasosartan; 145733-36-4; 2,4-dimethyl-8-{[2'-(2h-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-one; Tasosartan (USAN/INN); AC1Q6LAA; CHEMBL432162; D06010; S1539_Selleck; ANA-756; CHEBI:215967; AKOS000278114; DB01349; TASOSARTAN; Verdia; WAY-ANA-756; L001443; WAY-126756; 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[2,3-d]pyrimidin-7-one; AC1L1U5X; Pyrido(2,3-d)pyrimidin-7(6H)-one, 5,8-dihydro-2,4-dimethyl-8-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-
IndicationHypertension
[ICD9: 401   ICD10: I10, I11, I12, I13, I15]
Approved    [1]
Structure

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InChI1S/C23H21N7O/c1-14-18-11-12-21(31)30(23(18)25-15(2)24-14)13-16-7-
9-17(10-8-16)19-5-3-4-6-20(19)22-26-28-29-27-22/h3-10H,11-13H2,1-
2H3,(H,26,27,28,29)
InChIKeyADXGNEYLLLSOAR-UHFFFAOYSA-N
Canonical SMILESCC1=C2CCC(=O)N(C2=NC(=N1)C)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5    
Therapeutic ClassAntihypertensive Agents
CAS NumberCAS 145733-36-4
FormulaC23H21N7O
PubChem Compound IDCID 60919.
PubChem Substance IDSID 197148.
SuperDrug ATC IDC09CA05
SuperDrug CAS ID145733364;
TargetType-1 angiotensin II receptorAntagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Tasosartan, enoltasosartan, and angiotensin II receptor blockade: the confounding role of protein binding. J Pharmacol Exp Ther. 2000 Nov;295(2):649-54. To Reference



 

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