Therapeutic Targets Database
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TTD Drug ID: DAP001293

Drug Information
NameNitazoxanide
SynonymsSalicylamide, N-(5-nitro-2-thiazolyl)-, acetate (ester); Nitazoxanid; SMR000466367; N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester); Colufase; Daxon, Dexidex, Kidonax, Pacovanton, Paramix, Nitax, Zox, Nitazoxanide; Nitazoxanida; o-(N-(5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate; LS-144176; NSC 697855; Taenitaz; NSC697855; Daxon; Alinia; 2-Acetyloxy-N-[(5-nitro-2-thiazolyl)]benzamide; Nitazoxanida [INN-Spanish]; NCGC00090774-01; Alinia (TN); Nitazoxanidum; STK395664; NITAZOXANIDE; MolPort-002-042-244; azt+ nitazoxanide; CHEMBL1401; Benzamide, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-; Cryptaz; FT-0082459; I14-6011; Tizoxanide glucuronide; [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate; AC1Q5NVY; CID41684; C12H9N3O5S; SAM001246708; Nitazoxanide [USAN:INN]; D02486; ZINC03956788; EINECS 259-931-8; Nitazoxanide (USAN/INN); CPD000466367; Oprea1_263587; AC1L26A1; DB00507; 2-(Acetolyloxy)-N-(5-nitro-2-thiazolyl)benzamide; BRN 1225475; 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate; UNII-SOA12P041N; Phavic-1; (2-((5-Nitro-2-thiazolyl)carbamoyl)phenyl)acetat; AZT + Nitazoxanide; 55981-09-4; NCI60_034935; AC-1302; SBB068315; HMS2051L04; N-(5-Nitrothiazol-2-yl)salicylamide acetate ester; MLS000759492; Nitazoxanidum [INN-Latin]; MLS001424074; S1627_Selleck; NCIMech_000843; Heliton; 2-Acetyloxy-N-[(5-nitro-2-thiazolyl)]benzamide; Salicylamide, N-(5-nitro-2-thiazolyl)- acetate (ester)
Trade NameAlinia; Annita; Daxon; Dexidex; Kidonax; Pacovanton; Paramix; Nitax; Zox; Nitazox
CompanyUnimed Pharmaceuticals
IndicationDiarrhea
[ICD9: 787.91   ICD10: A09, K59.1]
Approved    [1]
Structure

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InChI1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)
15(18)19/h2-6H,1H3,(H,13,14,17)
InChIKeyYQNQNVDNTFHQSW-UHFFFAOYSA-N
Canonical SMILESCC(=O)OC1=CC=CC=C1C(=O)NC2=NC=C(S2)[N+](=O)[O-]    
Therapeutic ClassAntiparasitic Agents
CAS NumberCAS 55981-09-4
FormulaC12H9N3O5S
PubChem Compound IDCID 41684.
PubChem Substance IDSID 182380.
SuperDrug ATC IDP01AX11
P01AX11
TargetParasitic pyruvate:ferredoxin oxidoreductaseInhibitor[2]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 021497 To Reference
Ref 2Flavodoxin:quinone reductase (FqrB): a redox partner of pyruvate:ferredoxin oxidoreductase that reversibly couples pyruvate oxidation to NADPH production in Helicobacter pylori and Campylobacter jejuni. J Bacteriol. 2007 Jul;189(13):4764-73. Epub 2007 Apr 27. To Reference



 

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